📄 Category

medicine

6308 papers

📄 medicine

Neurosyphilis-associated longitudinally extensive transverse myelitis with severe bladder dysfunction and radiologic resolution: a case report

This case report describes a 31-year-old man with neurosyphilis presenting as longitudinally extensive transverse myelitis and severe bladder dysfunction, which was successfully diagnosed through specific serological testing and treated with ceftriaxone and corticosteroids, leading to complete radiologic resolution and significant clinical recovery.

Chih-Hsiang Wang, Yu-Cheng Chu2026-06-29
📄 medicine

ITGAM, MMP9 and THBS1 Define an Acute-Phase Extracellular Matrix-Immune Remodeling Module in Ischemic Stroke: An Integrated Multi-Cohort Transcriptomic Analysis Running title: ECM-immune module in acute ischemic stroke

This study identifies and validates a three-gene transcriptomic signature (ITGAM, MMP9, and THBS1) across multiple peripheral-blood cohorts that defines a coordinated acute-phase extracellular matrix-immune remodeling module, offering a potential biomarker for neurovascular inflammatory injury in ischemic stroke rather than immediate clinical diagnosis.

Bo-hui Zhang, Xuejing Wang, Kui Fan2026-06-29
📄 medicine

Prevalence and Prognostic Significance of Burst Suppression Patterns in Critically Ill Children - Comparison with Neurologically Healthy Controls

This study demonstrates that while a high burst suppression ratio (BSR) is an independent biomarker associated with increased mortality and poor functional outcomes in critically ill children, its poor standalone predictive accuracy limits its clinical utility to a complementary role within multimodal neuromonitoring frameworks rather than as an isolated prognostic tool.

Sandra Greve, Luisa Paul, Sophie Tillmanns, Habyna Ravichandrajah, Adela Della Marina, Ursula Felderhoff-Müser, Christia (…)2026-06-29
📄 medicine

Cholinergic Urticaria Triggered by Active Forced-Air Warming in the Post-Anesthesia Care Unit: A Case Report and Literature Review

This case report describes an 18-year-old male who developed cholinergic urticaria in the post-anesthesia care unit triggered by the synergistic effects of postoperative shivering and forced-air warming, highlighting the critical need to differentiate this condition from anaphylaxis and implement rapid non-pharmacologic cooling strategies.

Xin Zhou, Mengyu Zhang, Ping Zheng2026-06-29
📄 medicine

Workplace Safety Deficits and Healthcare Infrastructure Burden: A Regional Analysis of Occupational Injuries in Northeast Greece

This retrospective study of 385 occupational injuries in Northeast Greece reveals that a severe lack of safety training and a culture of blaming worker carelessness drive a disproportionate reliance on tertiary emergency care for fractures, resulting in significant economic losses and highlighting the urgent need for proactive, state-led preventive strategies.

Evdoxia Papazoglou, Eirini Deligiannidou, Christos Kontogiorgis, Grigorios Tripsianis, Evangelia Nena, Theodoros Konstan (…)2026-06-29
📄 medicine

An Interpretable Machine Learning Model for the Diagnosis of Coronary Heart Disease in Patients with Type 2 Diabetes Mellitus: A Multi-Center Cohort Study

This multi-center cohort study developed and validated an interpretable Gated Recurrent Unit (GRU) machine learning model using real-world data from 2,187 patients with type 2 diabetes, demonstrating robust performance in predicting coronary heart disease risk and identifying key predictors such as age, sex, and LDL-C to support early clinical screening and personalized interventions.

Yibo Lin, Xie Yanhong, Zheng Jianfeng, Yu Zhao, Zilong Wen, Junjie Zeng, Haibing Yu2026-06-29
📄 medicine

Health concerns of people who use unregulated stimulants: A qualitative study

This co-led qualitative study involving 27 participants in British Columbia identifies three core health concerns among people who use unregulated stimulants—navigating overdose risks, managing physical health consequences, and addressing co-occurring mental health conditions and neurodiversity—while emphasizing the critical need for tailored services and the meaningful involvement of people with lived experience in research and interventions.

Kaitlin Fajber, Jennifer Vincent, Sarah Ferrey, Juls Budau, Dylan Griffith, Charlene Burmeister, Amber Streukens, Elizab (…)2026-06-29
📄 medicine

Effect of an Eight-Weeks Yogic Intervention on Psychological Distress, Mental Well-being, and Physiological Regulation Among Teenage Student-Athletes: A Randomized Controlled Trial

This randomized controlled trial demonstrates that an eight-week structured yoga intervention significantly reduces psychological distress and improves mental well-being and physiological regulation, including resting heart rate and oxygen saturation, among competitive teenage student-athletes.

Sandeep Saroha, Deepak Bangari2026-06-29
📄 medicine

Does the Free-Handed Ball-Tipped Blunt Probe Improve Accuracy and Safety in Pedicular Screw Placement During Lumbar Spinal Fixation?

This prospective study of 90 patients demonstrates that the free-hand ball-tipped blunt probe technique ensures high accuracy (98.1%) and safety for lumbar pedicle screw placement while minimizing radiation exposure and avoiding neurological deficits related to screw breaches.

Morsy Basiony, Mahmoud Fahmy, Hesham Hamed Refae, Alaa Hasan, Moaaz Ali Hamoud, Ebeed Yasin2026-06-29