📄 Category

medicine

6308 papers

📄 medicine

Association Between a Novel MTV-Based Effective Absorbed Dose Index and ALBI Score Changes in Metastatic Colorectal Cancer Patients Treated with Yttrium-90 Glass Microspheres

This study demonstrates that a novel MTV-based Effective Absorbed Dose Index, derived from the ratio of tumour to non-tumoural liver absorbed doses, is significantly associated with stable liver function (ALBI score) in metastatic colorectal cancer patients treated with Yttrium-90 glass microspheres, suggesting its potential utility for optimizing individualized treatment planning and risk stratification.

Efe Soydemir, Şerife Çetin, Özlem Erez, Selin Kesim, Erbil Arık, Zeynep Ceren Balaban Genç, Ecem Ceran, Nihat Zümbül, Al (…)2026-06-28
📄 medicine

Standard guardrails impose a safety-critical omission tax on clinical large language models that a downstream verification layer reverses: a retrospective multi-cohort evaluation

This retrospective multi-cohort evaluation demonstrates that while standard guardrails reduce hallucinations in clinical large language models, they inadvertently increase safety-critical omissions, a trade-off effectively resolved by a downstream verification layer that restores omission rates to baseline levels without reintroducing commission errors.

Sanjay Basu, Sadiq Patel, Parth Sheth, John Morgan, Rajaie Batniji2026-06-28
📄 medicine

Evaluation of Various Obesity Indicators as Predictors of Elevated Blood Pressure in Chinese Adolescents

This study of over 10,000 Chinese adolescents found that while various obesity indicators are associated with elevated blood pressure, Z-scores of the new hip index (HI), body adiposity index (BAI), and waist-to-height ratio (WHtR) serve as the most significant independent predictors of this risk.

Weiwei Xiang, Lijuan Zheng, Xiang Liu, Xinwen Min, Chenghao Zhou, Handong Yang, Jun Chen, Jishun Chen, Dongfeng Li, Zhix (…)2026-06-28
📄 medicine

An Integrative Transcriptomic Analysis of a Stemness-Associated Gene Set on Ovarian Cancer Recurrence

This study identifies SOX2 and PROM1 as consistently upregulated stemness-associated genes in recurrent ovarian cancer through integrative transcriptomic analysis of TCGA and GEO datasets, validated by qRT-PCR, suggesting their critical role in the enrichment of cancer stem cell features driving disease relapse.

Ece Gumusoglu-Acar, Uygar Yucekaya, Sude Sultan Ozdemir, Samet Topuz, Tuba Gunel2026-06-28
📄 medicine

Safety of Minimally-Invasive Partial vs Radical Nephrectomy for cT1-T2 Renal Masses: An NSQIP Analysis

This NSQIP analysis of over 13,000 patients with cT1-T2 renal masses demonstrates that minimally-invasive partial nephrectomy is a safe alternative to radical nephrectomy, offering significantly lower risks of acute kidney injury, delayed bowel function, and prolonged hospital discharge without compromising outcomes regarding bleeding, reoperation, readmission, or mortality.

Jonathan Song, Nancy Donohoo, Samuel Lee, James Jones, Daniel Chen, Frank Meng, Mark Katz, David Wang2026-06-28
📄 medicine

Validation of Deep Capillary Plexus OCTA Metrics as Predictors of Diabetic Retinopathy Complications: A One-Year Longitudinal Study

This one-year longitudinal study validates that baseline deep capillary plexus vessel density measured by OCTA, alongside diabetic retinopathy severity and low-luminance visual acuity, serves as a significant independent predictor of vision-threatening complications in eyes with referable diabetic retinopathy, thereby improving risk stratification beyond traditional clinical models.

Julia Greenwood, Shinji Kakihara, Anna Busza, Amani Fawzi2026-06-28