6308 papers
This retrospective cohort study in the Central African Republic demonstrates that integrating psychosocial support into routine HIV care significantly improves retention in care and viral suppression rates among women living with HIV compared to standard care alone.
This systematic review of 27 studies highlights that while telemedicine offers significant potential to improve Sickle Cell Disease care globally, its effectiveness is currently hindered by infrastructure and economic disparities between developed and developing nations, necessitating a hybrid care model supported by strategic investments in digital infrastructure, affordability, and workforce training to ensure equitable access.
This bidirectional two-sample Mendelian randomization study utilizing European ancestry data found no causal evidence that genetically predicted serum 25-hydroxyvitamin D levels influence tuberculosis risk, suggesting the previously observed strong association is likely driven by confounding and reverse causation rather than a direct causal effect.
This study demonstrates that hospital waste incineration in Southwestern Nigeria significantly increases blood plasma concentrations of toxic heavy metals, particularly cadmium, mercury, lead, arsenic, and nickel, among exposed healthcare workers, with younger and female employees showing higher accumulation.
This case report describes a 45-year-old woman with a giant, hemorrhagic renal angiomyolipoma containing multiple pseudoaneurysms who was successfully treated with preoperative selective arterial glue embolization followed by total nephrectomy, highlighting the critical role of multimodal imaging and multidisciplinary management in preventing life-threatening complications.
This mixed-methods study reveals that while most of Cameroon's health information system data sources have defined standards, only 73% fully align with international benchmarks, with significant gaps in interoperability and capacity hindering the production of reliable data for strategic public health decision-making.
This systematic review and meta-analysis of Pakistani cancer cohorts reveals a distinctive TP53 mutational landscape characterized by a unique, population-enriched p.G244S variant in pancreatic ductal adenocarcinoma and highlights a critical data gap in hepatocellular carcinoma sequencing despite high regional risk factors.
This retrospective study demonstrates that femtosecond laser-assisted nanothin DSAEK guided by intraoperative OCT and pachymetric oversizing yields reproducible ultra-thin grafts with significantly better visual outcomes in successful cases, while identifying primary transplantation as a key predictor of success compared to re-transplantation.
This Bayesian network meta-analysis of 32 randomized controlled trials reveals that while Heller's Myotomy with Nissen Fundoplication and Pneumatic Dilation combined with Botulinum Toxin are the most effective interventions for treatment success and LES pressure reduction respectively, Anterior POEM also demonstrates high efficacy across both outcomes.
This systematic review and meta-analysis of eleven studies involving over 17,000 participants across seven African nations estimates a pooled pseudoexfoliation syndrome prevalence of 7.7%, though the finding is accompanied by extreme heterogeneity that suggests the rate varies significantly based on specific study settings, demographics, and geography rather than representing a uniform continental figure.