📄 Category

medicine

6308 papers

📄 medicine

Associations of hs-CRP and Interleukin-6 with Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study from Uzbekistan

This cross-sectional study from Uzbekistan demonstrates that elevated levels of high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) are independently associated with diabetic nephropathy in patients with type 2 diabetes, suggesting that chronic low-grade inflammation plays a significant role in the development of this kidney complication.

Olimjan Nazirkulov, Nigora Abdullayeva, Shukhrat Ziyadullaev, Dildora Tulyaganova, Avaz Kodirov, Jonibek Kadirov, Kamila (…)2026-06-28
📄 medicine

Prevalence and factors associated with non-communicable disease multimorbidity among adults in a rural block of Bihar, India: a community-based cross-sectional study

This community-based cross-sectional study in rural Bihar, India, found that 11% of adults aged 30 and above suffer from non-communicable disease multimorbidity, with older age, elevated blood glucose, increased body mass index, and physical inactivity identified as significant independent predictors.

ABHISHEK KUMAR, ALOK RANJAN, SANJAY PANDEY, PRAGYA KUMAR, AKASH P ZANWAR, NAVEEN SUTHAR2026-06-28
📄 medicine

Impact of Parenchymal Hemorrhage on Internal Carotid Artery Wall Shear Stress in Post-Traumatic Vasospasm: A Dynamic Helical CTA Study

This retrospective study demonstrates that post-traumatic cerebral vasospasm is associated with markedly elevated internal carotid artery wall shear stress, which is significantly amplified by the presence of non-surgical parenchymal hemorrhage, suggesting WSS as a potential biomarker for secondary brain injury risk.

Alexey O. Trofimov, Gregory N Vlasov, Kseniia A Trofimova, Ilya V Koshcheev, Dmitry A Martynov, Anastasia V Kivenko V An (…)2026-06-28
📄 medicine

From UK Metric to Nigerian Reality: Operationalizing the Standard Drink Concept for Alcohol Warning Labels under Current Packaging Bans

This perspective paper proposes adapting the UK's standard drink framework to Nigeria's post-packaging-ban landscape by calculating specific fluid volume thresholds for various alcohol categories and recommending mandatory front-of-pack warning labels and graduated dosing lines to help consumers adhere to safe daily consumption limits.

Christopher Enasor Fregene, Dike Bevis Ojji, Abimbola Opeyemi Adegboye2026-06-28
📄 medicine

Identifying key supports and barriers during the transition from pediatric to adult healthcare for individuals living with spinal muscular atrophy: A qualitative study

This qualitative study identifies that while multidisciplinary pediatric clinics effectively support individuals with spinal muscular atrophy, the transition to adult care is often hindered by a lack of specialized providers and mental health resources, highlighting the urgent need for structured adult multidisciplinary clinics and improved provider education to support patients with complex healthcare needs.

Elisa Lapadula, Sophia Ceulemans, Homira Osman, Emily Meier, Dylan Platt2026-06-28
📄 medicine

Validation of predictors rules for the need of pyeloplasty in cases of congenital pelviuretric like obstruction a prognostic study

This prognostic study of 35 pediatric patients with ureteropelvic junction obstruction demonstrates that the Pyeloplasty Prediction Score (PPS) offers superior diagnostic accuracy compared to the Hydronephrosis Severity Score (HSS) in predicting the need for pyeloplasty, with differential renal function and SFU grading identified as the most significant predictive variables.

Salma Abdelhady, Ahmed Abdelrasheed, Osama El-Naggar, Mostafa Elghandour, Mohamed Negm2026-06-28
📄 medicine

Histological Heterogeneity of SLFN11 Expression and Its Association with Response to Carboplatin Plus Paclitaxel Therapy in Salivary Gland Cancer

This study reveals that SLFN11 expression is heterogeneous and enriched in high-grade salivary gland cancers, where high expression levels are associated with numerically higher response rates to carboplatin plus paclitaxel therapy, suggesting its potential as an exploratory biomarker for platinum-based chemotherapy sensitivity, particularly in non-adenoid cystic carcinoma.

Satoshi Kano, Seijiro Hamada, Jun Taguchi, Nayuta Tsushima, Hiroshi Idogawa, Hayato Imanari, Masaki Kakumu, Mai Sakai, Y (…)2026-06-28
📄 medicine

Spatial Distribution of Urinary Schistosomiasis (USCH) in a Rural Community in Oyo State, Nigeria

This study in rural Otamokun, Nigeria, utilized GIS to map urinary schistosomiasis hotspots near water bodies and found that while infection prevalence decreases with distance from rivers, individual risk is likely driven by behavioral water-contact patterns rather than household proximity alone, necessitating a multi-pronged control strategy combining geographically targeted interventions with behavioral and sanitation improvements.

Taiwo Mofadeke JAIYEOLA, Zaidat Adesola. MUSA, Folahanmi Tomiwa AKINSOLU, Tubosun Alex OLOWOLAFE, Ekerette Emmanuel UDOH (…)2026-06-28
📄 medicine

Endocrine Manifestations of Kearns–Sayre Syndrome: A Systematic Review of Case Reports

This systematic review of 26 case reports highlights that endocrine dysfunction in Kearns–Sayre syndrome is a common, heterogeneous, and often progressive feature involving multiple glands, frequently preceding classical neurological symptoms and necessitating early multidisciplinary screening to improve patient outcomes.

Mahdia Babak, Savera khan, Muhammad Haris, Tolulope Joseph Ogunniy2026-06-28
📄 medicine

Validity of Angiography-Derived Microvascular Resistance in Hypertrophic Cardiomyopathy: A Head-to- Head Comparison With Pressure-Wire IMR

In patients with hypertrophic cardiomyopathy, angiography-derived microvascular resistance demonstrates moderate correlation and acceptable diagnostic accuracy for identifying microvascular dysfunction compared to invasive pressure-wire measurements, but its wide limits of agreement indicate it is not yet a reliable individual-level substitute for invasive assessment.

Louise Brunel, Nicolas Pioch, Benoit Caullery, Ikram El Marzouki, Gilles Barone-Rochette2026-06-28