📄 medicine

Prediction Model for Severe Complications in Patients with Failed Conservative Treatment of Acute Intestinal Obstruction Based on Clinical and Imaging Features: Development and Validation

This study developed and internally validated a prediction model combining clinical and CT imaging features to effectively identify patients with acute intestinal obstruction who are at high risk of developing severe complications after failing conservative treatment.

Mingjie Zhu, Jie Dan, Ming Li, Yonghong Wang, Wenjie Zhou, Ke Liu2026-06-25
📄 medicine

Neoaortoiliac System (NAIS) Reconstruction for Secondary Aortoenteric Fistula Following Infected Aortobiiliac Graft in a Patient with nonspecific aortitis

This case report describes the successful management of a secondary aortoenteric fistula caused by an infected aortobiiliac graft in a patient with nonspecific aortitis through emergent graft explantation, duodenal repair, and in-situ reconstruction using a neoaortoiliac system (NAIS) conduit derived from autologous femoral veins.

Tamer Fekry, Hatem Elamer, Ibrahim Fares Hegazy2026-06-25
📄 medicine

Fluoroscopic C-Arm Guided versus Ultrasound Guided Therapeutic Injection of Lower Cervical Radiculopathies

This study comparing ultrasound-guided selective cervical intra-tubercular nerve root blocks with fluoroscopic-guided cervical interlaminar epidural injections in patients with lower cervical radiculopathies found that while both methods provided similar pain relief and functional improvement at three months, the fluoroscopic group demonstrated superior long-term outcomes at six and twelve months.

Ahmed M.M. EL-Husseiny, Haitham H. Salem, Amr M. Abdelfatah, Mai A. Fathy, Nagia A. Fahmy, Ahmed M. EL-Sadek2026-06-25
📄 medicine

Lag-adjusted functional network connectivity reveals sensorimotor and higher cognitive network alterations in depression

By applying lag-adjusted functional connectivity analysis to resting-state fMRI data from 235 MDD patients and 284 healthy controls, this study reveals that depression is characterized not only by specific hyper- and hypo-connectivity patterns between sensorimotor and cognitive networks but also by a compressed inter-network timing that reflects altered neural coordination beyond simple connectivity strength.

Malvika Sridhar, Sir-Lord Wiafe, Zening Fu, Jing Sui, Vince Calhoun2026-06-25
📄 medicine

Temporal Trends in Sport Participation Among U.S. Children and Adolescents: Evidence from the 2016–2023 National Survey of Children’s Health

Based on data from the 2016–2023 National Survey of Children's Health, sport participation among U.S. children and adolescents declined significantly between 2016 and 2021 with a partial recovery by 2023, while persistent disparities across sex, race/ethnicity, and socioeconomic status highlight ongoing inequalities in access to sports opportunities.

Keyang Wang, Jie Fei2026-06-25
📄 medicine

TRAF3-Mediated Microglial Reprogramming by Time-Interferential Stimulation Enables Spatioselective Neuronal Rescue Post-Ischemia-Reperfusion 

This study demonstrates that non-invasive time-interferential stimulation (TIS) spatioselectively rescues neurons after ischemic stroke by disrupting the TRAF3-TBK1-NLRP3 axis to reprogram microglia from a pro-inflammatory M1 to an anti-inflammatory M2 phenotype, thereby mitigating cerebral ischemia-reperfusion injury.

Tao Xu, Tian Liu, Shunan Chen2026-06-25
📄 medicine

Cumulative C-reactive protein-triglyceride glucose index and its longitudinal trajectory in relation to incident cardiometabolic multimorbidity: the mediating role of body roundness index in middle-aged and older adults

This prospective cohort study of 8,464 middle-aged and older Chinese adults demonstrates that higher cumulative C-reactive protein-triglyceride glucose index (cuCTI) and unfavorable longitudinal CTI trajectories are independently associated with an increased risk of incident cardiometabolic multimorbidity, with body roundness index partially mediating this relationship.

Wen Xiao¹, Minxuan Wei, Yan Zeng2026-06-25
📄 medicine

Characteristics and Quality Assessment of Influenza-related Video on the Chinese Version of TikTok During an Epidemic Season: A Cross-Sectional Study

This cross-sectional study of 92 influenza-related videos on the Chinese version of TikTok during an epidemic season found that while overall content quality was moderate-to-high with news organizations outperforming physicians, user engagement metrics failed to predict quality, whereas video length and uploader follower count emerged as significant positive predictors.

Xiaofang Jiang, Feng Yu, Jingbang Liu, Jiahan Hu, Meng Wang, Shina Qiao, Jinhang Xu, Lili Wu2026-06-25