📄 Category

medicine

6385 papers

📄 medicine

Lag-adjusted functional network connectivity reveals sensorimotor and higher cognitive network alterations in depression

By applying lag-adjusted functional connectivity analysis to resting-state fMRI data from 235 MDD patients and 284 healthy controls, this study reveals that depression is characterized not only by specific hyper- and hypo-connectivity patterns between sensorimotor and cognitive networks but also by a compressed inter-network timing that reflects altered neural coordination beyond simple connectivity strength.

Malvika Sridhar, Sir-Lord Wiafe, Zening Fu, Jing Sui, Vince Calhoun2026-06-25
📄 medicine

Temporal Trends in Sport Participation Among U.S. Children and Adolescents: Evidence from the 2016–2023 National Survey of Children’s Health

Based on data from the 2016–2023 National Survey of Children's Health, sport participation among U.S. children and adolescents declined significantly between 2016 and 2021 with a partial recovery by 2023, while persistent disparities across sex, race/ethnicity, and socioeconomic status highlight ongoing inequalities in access to sports opportunities.

Keyang Wang, Jie Fei2026-06-25
📄 medicine

TRAF3-Mediated Microglial Reprogramming by Time-Interferential Stimulation Enables Spatioselective Neuronal Rescue Post-Ischemia-Reperfusion 

This study demonstrates that non-invasive time-interferential stimulation (TIS) spatioselectively rescues neurons after ischemic stroke by disrupting the TRAF3-TBK1-NLRP3 axis to reprogram microglia from a pro-inflammatory M1 to an anti-inflammatory M2 phenotype, thereby mitigating cerebral ischemia-reperfusion injury.

Tao Xu, Tian Liu, Shunan Chen2026-06-25
📄 medicine

Cumulative C-reactive protein-triglyceride glucose index and its longitudinal trajectory in relation to incident cardiometabolic multimorbidity: the mediating role of body roundness index in middle-aged and older adults

This prospective cohort study of 8,464 middle-aged and older Chinese adults demonstrates that higher cumulative C-reactive protein-triglyceride glucose index (cuCTI) and unfavorable longitudinal CTI trajectories are independently associated with an increased risk of incident cardiometabolic multimorbidity, with body roundness index partially mediating this relationship.

Wen Xiao¹, Minxuan Wei, Yan Zeng2026-06-25
📄 medicine

Characteristics and Quality Assessment of Influenza-related Video on the Chinese Version of TikTok During an Epidemic Season: A Cross-Sectional Study

This cross-sectional study of 92 influenza-related videos on the Chinese version of TikTok during an epidemic season found that while overall content quality was moderate-to-high with news organizations outperforming physicians, user engagement metrics failed to predict quality, whereas video length and uploader follower count emerged as significant positive predictors.

Xiaofang Jiang, Feng Yu, Jingbang Liu, Jiahan Hu, Meng Wang, Shina Qiao, Jinhang Xu, Lili Wu2026-06-25
📄 medicine

The role of cancer fatalism in delayed health-seeking behavior among colorectal cancer patients in China: a cross-sectional analysis of psychosocial and socioeconomic determinants

This cross-sectional study of 126 colorectal cancer patients in China reveals that strong cancer fatalistic beliefs and advanced tumor stage are significant independent predictors of delayed health-seeking behavior, highlighting the need for targeted interventions to improve early detection.

Yuqin Tan, Ziqi Lin, Yuxiang Xi, Dongyan Zeng, Rongfei Suo, Shili Chen2026-06-25
📄 medicine

Household HIV competence and illness identity in HIV: Insights from the baseline phase of the SINAKO cluster randomised controlled trial

This study from the SINAKO trial demonstrates that higher household HIV competence is significantly associated with greater acceptance and lower rejection of HIV as part of one's identity, highlighting the critical role of family support in shaping the illness experience of people living with HIV.

Neo Sematlane, Linda Campbell, Caroline Masquillier, Edwin Wouters, Lucia Knight2026-06-25
📄 medicine

The Composite Deformity Score (CDS): Development and Preliminary Assessment of a Radiographic Scoring System for Assessing Osteochondral Lesion Severity of the Talus

This study developed and preliminarily validated the Composite Deformity Score (CDS), a highly reliable five-parameter radiographic index that significantly correlates with osteochondral lesion severity and size in the talus, demonstrating strong predictive value and location-specific patterns that warrant further multicenter validation.

Moaaz Ali Hamoud, Ahmed Swealem, Mohamed Hatata2026-06-25
📄 medicine

Use of Cannabidiol as a prophylactic treatment in acute mesenteric ischemia

This study demonstrates that prophylactic treatment with cannabidiol (CBD) significantly mitigates local intestinal and systemic hepatic damage caused by ischemia-reperfusion injury in rats of different ages by reducing inflammation, oxidative stress, and apoptosis while preserving tissue architecture and function.

Salomón José Marea-Peñalver, Lucía Íñigo-Catalina, María Ortiz-Cabello, Sira Iturrizaga Correcher, Ignacio Garcia-Alonso (…)2026-06-25