6597 papers
A retrospective review of 79 NASA astronauts reveals that post-landing orthostatic intolerance is frequently treated with highly variable, non-standardized intravenous fluid volumes lacking evidence-based guidelines, highlighting an urgent need for physiology-informed protocols for future deep-space missions.
This study introduces the Quantified Epidemic Energy (QEE) model, a novel stochastic framework that integrates climate risk and reporting delays to accurately forecast cholera incidence in Yemen's Al-Hodeidah Governorate, offering a robust, uncertainty-quantified tool for proactive early-warning systems in data-scarce, conflict-affected settings.
This case report demonstrates that intravenous infusion of allogeneic adipose-derived mesenchymal stem cells is a safe and effective intervention that significantly improved clinical symptoms, normalized liver enzymes, and halted disease progression in a 69-year-old patient with end-stage liver cirrhosis, offering a promising alternative to liver transplantation.
This retrospective cohort study of 173 patients undergoing stereotactic biopsy for suspicious mammographic microcalcifications found that malignancy was present in 21.4% of cases and identified regional and linear distribution patterns, along with pleomorphic morphology, as independent predictors of malignancy.
This study presents a deep-learning pipeline that achieves fully automated DMFT determination from panoramic radiographs with overall agreement comparable to that between human dentists, demonstrating strong performance for identifying missing and filled teeth while highlighting persistent challenges in detecting decayed teeth due to the limitations of panoramic imaging.
This longitudinal study demonstrates that urinary metabolomics can identify a specific metabolic signature associated with muscle injury and recovery in elite football players, offering a promising non-invasive tool to complement external load monitoring for individualized athlete assessment.
This paper introduces a "spring-plane" model demonstrating that even modest reductions in lumbar lordosis cause superlinear increases in anterior disc stress through coupled mechanical mechanisms, providing a quantitative rationale for preserving segmental lordosis to mitigate L4-L5 disc degeneration.
This study demonstrates that the BRAFV600E mutation confers cisplatin resistance in colorectal cancer by suppressing ferroptosis through the NF-κB/Lipocalin 2 signaling pathway, suggesting that restoring LCN2 expression could overcome this therapeutic resistance.
This paper presents VEN-1, a programmable hybrid nanobot platform combining DNA origami, nanocarbon resistance sensing, and magnetic propulsion to physically extract mutating viruses from host tissue upon reaching a specific binding threshold, offering a mutation-resistant therapeutic alternative to conventional antivirals.
This mixed-methods study of Community Led Complementary Feeding and Learning Sessions in three disaster-prone districts of Malawi reveals that while knowledge transfer enabled over 60% of households to sustain practices post-project, long-term continuity ultimately depends on addressing resource constraints, labor intensity, and the strength of community committees through localized resilience strategies.