medicine papers | Gist.Science

Impact of robotic access and dedicated kidney surgery teams on nephron-sparing surgery for T1 renal masses: Evidence from a Spanish multicenter registry

Based on a Spanish multicenter registry, access to robotic-assisted surgery significantly increased the utilization of partial nephrectomy for T1 renal masses—particularly cT1b tumors—while dedicated kidney surgery teams were associated with fewer cases recorded as technically infeasible despite not independently increasing partial nephrectomy rates after stratification.

Itzhak Testa Sklofsky, Daniel Pérez-Fuentes, Inmaculada Bravo Fernández, Mario De Arriba Alonso, Diego Roberto Ballester (…)2026-06-25

📄 medicine

Thymoquinone induces ROS generation and apoptosis in A549 lung cancer cells

This study demonstrates that Thymoquinone (TQ) exerts anticancer effects on A549 lung cancer cells by inducing ROS-mediated apoptosis and downregulating the mRNA expression of STAT3 target genes, suggesting its potential as a therapeutic agent for lung cancer.

Reza Farsiabi, Iraj Khodadadi, Jamshid Karimi, Gholamreza Shafiee2026-06-25

📄 medicine

Hematoprotective and Genoprotective Effects of Graded Vitamin C Supplementation in Benzene-Induced Pre-Leukemic Rats

This study demonstrates that graded oral supplementation of vitamin C (100–1000 mg/kg) provides potent, dose-dependent hematoprotective and genoprotective effects against benzene-induced bone marrow failure, pancytopenia, and pre-leukemic changes in rats, with the highest dose effectively restoring blood parameters and reducing circulating blasts to near-control levels.

Laveena Anand Masih2026-06-25

📄 medicine

Methodological approaches to developing clinical prediction models to predict multiple long-term conditions, a systematic review

This systematic review of three studies published since 2023 reveals that while various complex methodologies have been applied to predict multiple long-term conditions, the field remains nascent and limited by high risk of bias, sub-optimal validation practices, and a lack of external validity, highlighting an urgent need for further rigorous investigation and methodological comparison.

Lauren A Anderson, Clare L Gillies, Joie Ensor, Kamlesh Khunti, Selina T Lock, Naomi Bradbury, Louise Haddon, Hannah Wor (…)2026-06-25

📄 medicine

Scoping Review of Post-Acute COVID-19 Syndrome: Is it COVID-19 Virus or the Vaccines?

This scoping review aims to synthesize global evidence to determine whether Post-Acute COVID-19 Syndrome (PACS) is more closely associated with the SARS-CoV-2 virus or COVID-19 vaccinations, utilizing the JBI protocol and PRISMA-ScR guidelines to analyze data from multiple major databases and health organizations.

Isaac K. Agbenyezi, Mercy D. Quarm, Patrick L. K. Fianu, Elizabeth Dudjin, Edward W. Ansah2026-06-25

📄 medicine

Advanced Spatial Clustering for Mapping Child Stunting and WaSH Determinants in Low and Middle Income Countries

This scoping review synthesizes evidence demonstrating that advanced spatial clustering methodologies reveal critical subnational inequalities in child stunting driven by WaSH determinants, arguing that shifting from national averages to high-resolution precision mapping is essential for optimizing targeted global health interventions.

Mutia Ramadhani, Moses Glorino Rumambo Pandin2026-06-25

📄 medicine

Breast Cancer Recurrence Prediction: A High-Performance Deep Learning Approach on Clinical Data

This study presents a high-performance deep learning model using the METABRIC dataset that achieves a new benchmark in breast cancer recurrence prediction by attaining 100% precision, thereby demonstrating that sophisticated data engineering and network architecture can outperform complex multi-modal approaches even with limited clinical data.

Mohammad2026-06-25✓ Author reviewed ⓘ

📄 medicine

All-cause mortality patterns according to vaccination timing and dose number among Japanese non-elderly adults: a proxy risk-group analysis

This study of non-elderly adults in Matsudo City, Japan, found that while confounding by indication influenced early mortality patterns, all-cause mortality rates generally increased with the number of COVID-19 vaccine doses, even among proxy high-risk groups, suggesting that the observed trends are not fully explained by bias alone.

Hideki Kakeya, Hiroshi Kusunoki, Yumi Watanabe, Ryota Sakai2026-06-25

📄 medicine

Work-Related Low Back Pain and Associated Factors Among Healthcare Workers in Dire Dawa Administration, Eastern Ethiopia

A facility-based cross-sectional study conducted in Dire Dawa, Eastern Ethiopia, found that nearly 30% of healthcare workers suffer from work-related low back pain, with significant risk factors including age over 40, work experience exceeding five years, prolonged standing, heavy lifting, alcohol consumption, and a lack of regular work breaks.

Shiferaw Letta2026-06-25

📄 medicine

Prior Incarceration and Cognitive Impairment in the United States: A Scoping Review

This scoping review of nine recent observational studies finds that prior incarceration in the United States is consistently associated with an elevated risk of cognitive impairment and poorer cognitive performance among community-dwelling adults, although these associations are often attenuated by factors such as educational attainment and premorbid cognition.

Alexander Testa, Chelsea Carriker, Karyn Fu, Sandra Desjardins, Ava Yoder, Rhea Ray, Krishna Chandrasekhara, Jiaming Lia (…)2026-06-25

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