📄 medicine

Clinical Study on Early Conservative Tangential Excision Combined with Xenogeneic Dermal Grafting for the Treatment of Extensive Critical Burns

This study demonstrates that performing conservative tangential excision combined with xenogeneic dermal grafting within 12 to 24 hours post-burn for extensive critical burns effectively maintains hemodynamic stability, reduces fluid resuscitation needs and systemic inflammation, and improves clinical outcomes by lowering infection rates, surgical requirements, and hospital stay duration.

Jun Liu, Ruo Nan Lu, Hui Wang, Da Wang2026-07-15
📄 medicine

Surgical Decision-Making and Treatment Response in Invasive Lobular Carcinoma Treated with Primary Surgery or Neoadjuvant Therapy

This retrospective study of 104 invasive lobular carcinoma cases reveals that neoadjuvant systemic therapy yields limited pathological response and fails to significantly increase breast-conserving treatment rates compared to primary surgery, highlighting the challenges of managing ILC's distinct biological features.

Margit Riis, Carlos Casas Arozamena, Jon Lømo, Ole Christian Lingjaerde, Jens Henrik Norum2026-07-15
📄 medicine

Associations between the TyG index and the TG/HDL-C ratio with hypertension in Chinese women: a cross-sectional study

This cross-sectional study of over 52,000 Chinese women demonstrates that higher TyG index and TG/HDL-C ratio levels are independently and positively associated with hypertension, exhibiting non-linear dose-response relationships with identified clinical thresholds of TyG > 8.0 and TG/HDL-C > 1.4 that could serve as effective, low-cost screening tools for early risk identification.

Zhou Liu, Yi Yang2026-07-15
📄 medicine

Intrinsic Capacity Index and Cross-sectional Associations with Geriatric Outcomes in Community- Dwelling Older Adults

This cross-sectional study developed and validated a feasible Intrinsic Capacity Index (ICI) based on the WHO ICOPE framework, demonstrating that lower ICI scores in community-dwelling older adults are significantly associated with adverse geriatric outcomes such as frailty, functional dependence, and polypharmacy.

Lucía Sáez-González, Lucía Castro-Vázquez, Luis A. Martínez, José Antonio Carbajal de Lara, Rosa M. Martinez-Garcia, G. (…)2026-07-15
📄 medicine

Knowledge Attitudes and Practices Regarding Artificial Intelligence in Healthcare Among Medical Undergraduates at a Private Medical Institute in Delhi NCR

This cross-sectional study of 365 medical undergraduates in Delhi NCR reveals that while students exhibit moderate knowledge, neutral attitudes, and growing engagement with AI tools like ChatGPT, significant gaps in formal training and practical competency persist, underscoring the urgent need for structured curricular integration of AI literacy and ethics in medical education.

GEETIKA SINGH, Tanya Khanna, Riya Malhotra2026-07-15
📄 medicine

Evaluating the Impact of a Medical Consortium-Based Continuing Medical Education Program on Improving COPD Knowledge Among Primary Care Physicians in Jinjiang District, Chengdu: A Pre-Post Intervention Study

This pre-post intervention study demonstrates that a medical consortium-based continuing medical education program significantly enhanced COPD-related knowledge and clinical skills among 296 primary care physicians in Jinjiang District, Chengdu, validating its potential as a scalable model for strengthening chronic respiratory disease management in primary care.

Yeran Gou, Xiaobo Hu, Yongsheng Wang, Zhengxu Deng, Yanmei Wen, Jiachen Lin2026-07-15
📄 medicine

Integrated In Vivo Optical Coherence Tomography and Metabolomics in a Rabbit Model Identify Specific Metabolic Dysregulation Underlying In-Stent Neoatherosclerosis

This study utilizes integrated in vivo optical coherence tomography and untargeted metabolomics in a rabbit model to identify specific metabolic dysregulations, including altered levels of 11 key metabolites and their interaction with the Slc5a7 receptor, that underlie the progression of in-stent neoatherosclerosis.

Yan Fang, Xiawa Wang, Lei Fan, Shi Feng, Huimin Liu, Shaohong Fang, Fuman Du, Zhuozhong Wang2026-07-15
📄 medicine

Microbiota Transplant Therapy (MTT) Improves Gastrointestinal Symptoms in Children with Pitt-Hopkins Syndrome: A Randomized Clinical Trial

This randomized clinical trial demonstrates that microbiota transplant therapy is safe and effectively improves gastrointestinal symptoms and behavioral outcomes in children with Pitt-Hopkins syndrome by remodeling the gut microbiome and enhancing mitochondrial function.

Rosa Krajmalnik-Brown, James Adams, Evelyn Takyi, Manish Muchapothula, Jasmine Kirby, Carlos Robles, Emerson Fongenyam (…)2026-07-15
📄 medicine

Knowledge, Attitudes and Practices Regarding Mpox Among Health Professionals in Beira City, Central Mozambique: A Cross-Sectional Study

This cross-sectional study of 563 healthcare professionals in Beira City, Mozambique, reveals that while the majority hold favorable attitudes toward Mpox, knowledge levels are moderate and significantly influenced by age, education, professional role, and access to multiple information sources, highlighting the need for targeted training and improved surveillance integration.

Caetano Topola Raposo, Agnélio da Silva, Unicia Nyamula, Jaime Fernando, Marcelino Piquete, João Luís Manuel, Edi Fulai (…)2026-07-15