📄 medicine

Sex differences in pregnancy complications and autism

This study utilizing Swedish birth registry data reveals that while male pregnancies are generally more prone to complications, the link between these complications and autism is largely independent of fetal sex, with prematurity and other factors consistently associated with autism across both sexes, ultimately identifying fetal sex as the strongest predictor of autism likelihood.

Alex Tsompanidis, Johanna Sieurin, Cecilia Magnusson, Simon Baron-Cohen, Kyriaki Kosidou2026-10-20
📄 medicine

Postpartum Depressive Symptoms and Associated Risk Factors Among Women Undergoing Caesarean Delivery at a Tertiary Care Centre in New Delhi, India: A Prospective Observational Study

This prospective observational study of 350 women in New Delhi undergoing caesarean delivery found that postpartum depressive symptoms were prevalent (18.3% over six months) and significantly associated with risk factors including family history of psychiatric illness, intimate partner violence, lack of social support, multiparity, elective caesarean delivery, and postoperative complications, underscoring the need for integrated screening and targeted mental health support in postnatal care.

Shweta Varun, Pratima Mittal, Rekha Bharti, Bhagyashree Singh, Garima Singh, Pankaj Verma, Abhishek Lachyan2026-10-20
📄 medicine

Study protocol for a hybrid type III effectiveness-implementation evaluation of the Detecta-APS strategy for organized breast and cervical cancer screening in Brazilian primary health care

This study protocol outlines a hybrid type III effectiveness-implementation evaluation using a multi-methods design to assess the DETECTA-APS strategy's role in transitioning Brazil's primary health care from opportunistic to organized breast and cervical cancer screening, with the goal of identifying implementation determinants and informing context-sensitive adaptations to improve access and outcomes.

Talita dos Santos Rosa, Andressa Rocha Olah, Ilana Eshriqui Oliveira, Leticia Yamawaka de Almeida, Talita Rewa, Marilia (…)2026-10-20
📄 medicine

Socioeconomic status and high impact chronic pain among adults in the United States: analysis of the 2016 National Health Interview Survey

This cross-sectional analysis of the 2016 National Health Interview Survey reveals that lower socioeconomic status is independently associated with significantly higher odds of high-impact chronic pain among U.S. adults, highlighting the need for interventions that address educational, employment, and poverty-related inequalities alongside clinical management.

Korin Neh Nforbi, Isaac Obeng Gyasi, Bibiana Frans-Asmah, Philip Obiri Ankomah, Susan Onumanyiwa Nyanteh, Abigail Obeng (…)2026-10-20
📄 medicine

Ameliorative Effect of PRF and Silver Hydroxyapatite Nanoparticles bio-composite on femoral head AVN in a Rat Model

This study demonstrates that a local bio-composite of silver hydroxyapatite nanoparticles and platelet-rich fibrin significantly promotes osteogenesis, angiogenesis, and structural repair in a rat model of early-stage femoral head avascular necrosis, effectively preventing joint collapse and degeneration compared to control treatments.

Aml Awad, Awad Rizk, Mohamed ElAlfy, Mohamed Hamed, Amr M. Abdelghany, Hussain Noorwali, Esam Mosbah, Adel Zaghloul, Gam (…)2026-10-20
📄 medicine

Spatiotemporal Clustering of Tuberculosis Incidence and Identification of Hotspots in Bobonaro Municipality, Timor-Leste: A Five-Year Ecological Study (2021–2025)

This five-year ecological study of Bobonaro Municipality, Timor-Leste, reveals that while tuberculosis incidence exhibited significant spatial clustering in 2023 and 2024, the lack of consistent global autocorrelation across all years highlights the temporal heterogeneity of disease patterns and underscores the value of local spatial analysis for identifying priority areas for targeted surveillance.

Zito Viegas Cruz, Filipe Neri Machado, José Araujo Amaral2026-10-20✓ Author reviewed ⓘ
📄 medicine

Beyond AUROC: External Validation, Calibration, and Explainability of Machine Learning Models for 30-Day Hospital Readmission Using Electronic Health Records—A Rapid Systematic Review

This rapid systematic review of 156 studies reveals that machine learning models predicting 30-day hospital readmission overwhelmingly rely on AUROC as the sole performance metric while critically neglecting essential evaluations of external validity, calibration, and explainability, prompting a call for a more rigorous "beyond AUROC" assessment framework.

Md Eftakhar Ahamed, Md. Istiakul Alam, Mohammad Shamsul Arefin2026-10-20
📄 medicine

Can Daily Drills of Ventilation Corrective Steps Improve Mask Ventilation of Preterm Infants in the Delivery Room? – A Randomized Controlled Trial

This randomized controlled trial demonstrates that brief, daily simulation drills of MR SOPA ventilation corrective steps significantly reduce mask leak during positive pressure ventilation in delivery room resuscitations of preterm infants compared to self-directed review of the NRP algorithm.

Emediong E. Idung, Megan O’Reilly, Po-Yin Cheung, Georg M. Schmölzer2026-10-20