📄 medicine

Comparison of early postoperative activity-related pain burden after conventional, navigation-assisted, and robotic-assisted total knee arthroplasty: a retrospective cohort study based on 24-72 h pain area under the curve

This retrospective cohort study of 169 patients found that while both navigation-assisted and robotic-assisted total knee arthroplasty reduced early movement-related pain compared to conventional techniques, robotic-assisted surgery demonstrated the lowest cumulative pain burden from 24 to 72 hours postoperatively.

Yan XU, Weiqing Li, Yiwei Song, Wei Xu, Chang She, Shendong Wang2026-06-26
📄 medicine

Título Del Artículo (Inglés): 3d Printed Supramesocolic Laparoscopic Simulator for the Choledochoduodeno Anastomosis: Proposal for a Model

This study proposes and validates a 3D-printed supramesocolic laparoscopic simulator for choledochoduodenostomy, demonstrating that repeated practice on the model significantly improves surgical skills and reduces procedure time.

Miguel Vassallo Palermo, Aquiles Ramón Molero Chacón, José Leonardo Morao Pompilli, Alexis Oliveros Grimán2026-06-26✓ Author reviewed
📄 medicine

Prevalence and phenotypic profiles of ESBL-producing Escherichia coli across the human-animal-environment sectors: a multi-sectoral surveillance during the first year of implementation of the Tricycle project in Burkina Faso

This multi-sectoral surveillance study in Burkina Faso reveals a high and varied prevalence of ESBL-producing *Escherichia coli* across human, animal, and environmental sectors, with blood culture isolates showing the highest antibiotic resistance, thereby underscoring the urgent need for enhanced hygiene, integrated surveillance, and rational antibiotic use under the One Health approach.

Hervé Kafando, Merci Muhigwa, Milen Milenkov, Odilon Dieudonné Kaboré, André Nagalo, Marie-Noëlle Didelot, Ibrahim Guing (…)2026-06-26
📄 medicine

Influenza-Associated Neurological Complications in Pediatric Patients: Clinical Characteristics, Outcomes, and Risk Stratification Using the Neuroinfluenza Severity Score  from the Multicenter TURK-INF Study

This multicenter study of 397 pediatric patients in Türkiye characterizes the clinical spectrum of influenza-associated neurological complications, finding that seizures are the most common manifestation with high recovery rates, and validates the Neuroinfluenza Severity Score (NISS) as a highly accurate tool for predicting poor outcomes and guiding early risk stratification.

Sevgi Kuş, Şilem Özdem Alataş, Gülşen Akkoç, Sevliya Öcal Demir, Mustafa Gençeli, Murat Sütçü, Sema Yıldırım Arslan, Esr (…)2026-06-26
📄 medicine

Creating Clinically Labeled MIMIC-III PPG Datasets for CAD and CVD Research: A Reproducible Workflow

This paper presents a reproducible workflow for constructing clinically labeled photoplethysmography (PPG) datasets from MIMIC-III, yielding distinct coronary artery disease (CAD) and broader cardiovascular disease (CVD) cohorts with quality-screened waveforms and patient-level clinical annotations to support future cardiovascular research.

Raghunath Reddy, Gautam Kumar, Veeranjaneyulu R2026-06-26
📄 medicine

Predictive Factors of Castration Resistance in Prostate Cancer in Guinean Men : A Retrospective Study of 90 Cases

This retrospective study of 90 Guinean men with advanced prostate cancer identifies a high ISUP score (≥3) as the sole independent predictor of developing castration resistance, underscoring the critical need for early histological diagnosis and prognostic stratification in this population.

MORLAYE FATOUMATA BANGOURA, DEMBA CISSE, ALPHA OUMAR BARRY, YOUSSOUF KEITA, MAMOUDOU BALDE, MAMADOU DIAWO BAH, THIERNO M (…)2026-06-26
📄 medicine

Measuring Quality of Life in Children with Lower-Limb Differences: German Translation and Validation of the GOAL-LD™

This study successfully translated and culturally adapted the Gait Outcomes Assessment List for Children with Lower-Limb Difference (GOAL-LD™) into German, demonstrating its excellent internal consistency and readiness for use in clinical practice and research to assess health-related quality of life in German-speaking children with lower-limb differences.

Bjoern Vogt, Leona Seifert, Georg Gosheger, Robert Roedl, Jan Duedal Rölfing, Anna-Kathrin Hell, Unni G. Narayanan, Greg (…)2026-06-26
📄 medicine

Equity and Efficiency of Healthcare Resource Allocation in Shanghai, China: A Longitudinal Study from 2009 to 2024

This longitudinal study of Shanghai from 2009 to 2024 reveals that while healthcare resource expansion has successfully improved population-based allocation equity, it has simultaneously exacerbated spatial and intra-district inequalities while reducing overall efficiency due to technological regression and urban-suburban structural mismatches, necessitating a strategic shift from scale-driven growth to quality-oriented development.

Xiuzhi Chen2026-06-26
📄 medicine

COVID-19 Pandemic Changes Epidemiology, Clinical Features and Laboratory Markers of Epstein-Barr Virus Infection in Children: A Three-Period Retrospective Study of 438 Cases

This retrospective study of 438 hospitalized Chinese children reveals that the COVID-19 pandemic significantly altered the epidemiology, clinical severity, and laboratory profiles of Epstein-Barr virus infections, shifting the pattern from primary infections during strict containment to increased viral reactivation and severe complications in the post-pandemic period.

Zheng Zhang¹⁺,, Tao Zhan²⁺,, Jiahui Hu2026-06-26