📄 Category

medicine

6783 papers

📄 medicine

Limited discriminative utility of resting-state heart rate variability for chronic pain–depression–anxiety comorbidity subtypes: an exploratory SHAP-based machine-learning analysis

This exploratory study utilizing SHAP-based machine learning found that resting-state heart rate variability has limited and unstable discriminative utility for distinguishing chronic pain–depression–anxiety comorbidity subtypes, particularly pain-depression and pain-anxiety dominant presentations, suggesting it is insufficient as a standalone biomarker for such classification.

Tian Xie, Jinchao Hu, Xin Tian, Guangyuan Ma, Jingchi Li, Jiexiang Yang, Yi Chen, Cheng Luo2026-06-28
📄 medicine

A Modified Lateral Skin Incision Reduces Wound Complications and hospital stay in Obese patients undergoing Total Knee Arthroplasty: A Propensity-Matched Cohort

This propensity-matched cohort study demonstrates that in morbidly obese patients undergoing total knee arthroplasty, a modified curved lateral skin incision significantly reduces wound complications, shortens hospital stays, and decreases anterior knee hypesthesia compared to the standard midline approach, while maintaining equivalent long-term functional outcomes.

Ahmed Saeed Younis, Sherif Mostafa Abdeldayem, Ibrahim Mahmoud Abdelmonem2026-06-28
📄 medicine

Clinical study on guidance of the timing of adaptive replanning for cervical cancer based on ADC values combined with tumor volume regression

This study demonstrates that early increases in apparent diffusion coefficient (ΔADC) during concurrent chemoradiotherapy for cervical cancer are strongly associated with tumor volume regression and can help identify patients for adaptive replanning, although replanning at the 15th fraction did not consistently offer dosimetric advantages over the 20th fraction.

YU QIAN MA, JIAXU yan, WENFEI li, DEFENG liu, LIYAN cao, YU MAO, LIJIE LIU, TAO GU2026-06-28
📄 medicine

Effectiveness of lay counselor-delivered intervention for trauma-related symptoms in conflict- affected populations: a cluster randomized trial in Iraq

This cluster randomized trial conducted in Iraq demonstrates that a single session of lay counselor-delivered thought field therapy significantly reduces trauma-related symptoms and PTSD prevalence among displaced women compared to relaxation therapy, supporting its potential as an effective community-based intervention in conflict-affected settings.

Pegah Seidi, Dilshad Jaff, Linda Tawfik, Suzanne Connolly2026-06-28
📄 medicine

Mortality and Renal Impairment in Critically Ill Patients across world regions over 2007 to 2024: a nutritionDay descriptive multivariable analysis

This large international multivariable analysis of over 23,000 critically ill patients from 2007 to 2024 identifies renal replacement therapy, advanced age, and illness severity as the strongest independent predictors of 60-day hospital mortality, while highlighting that the association between renal impairment and outcomes varies significantly based on the underlying disease causing ICU admission.

Arabella Fischer-Hammerschmied, Peter Bauer, Fiona Trumshi, Silvia Tarantino, Emir Softic, Christian Schuh, Sylvia Ryz (…)2026-06-28
📄 medicine

Triglyceride-glucose waist-to-height ratio and risk of arthritis among middle- aged and older Chinese adults: a national cohort study

This national cohort study of 5,372 middle-aged and older Chinese adults demonstrates that elevated triglyceride-glucose waist-to-height ratio (TyG-WHtR) is independently and linearly associated with an increased risk of incident arthritis, suggesting it serves as a practical clinical tool for early risk stratification.

Jinyu Zhu, Wei Wang, Yun Bo, Yichao Liu, Ye Ding, Fangyi Chen, Chenze Zhan, Haining Qi, Yuanyuan Zhang, Xiaoxiao Wang, P (…)2026-06-27