📄 medicine

The Hormone-Brain-Emotion Axis in Endocrine Therapy for Early Breast Cancer: Insights from a Survivorship Cohort

This study of women undergoing adjuvant endocrine therapy for early breast cancer reveals that fatigue and emotional distress are the primary, interrelated drivers of perceived cognitive impairment, suggesting that routine screening and management of these modifiable symptoms are essential for improving survivorship care and treatment adherence.

Tiago Pina-Cabral, Vanessa Branco, Patricia Cavaco, Margarida Lagarto, José Pereira, Helena Miranda, Ana Martins2026-06-28
📄 medicine

Prevalence of obstructive sleep apnoea and validation of the OSA-5 questionnaire among children aged 2-7 years with adenotonsillar hypertrophy at Mulago National Referral Hospital, Uganda: a prospective cross-sectional study

This prospective cross-sectional study at Mulago National Referral Hospital found that obstructive sleep apnoea affects 88.5% of children aged 2–7 with adenotonsillar hypertrophy and demonstrated that the OSA-5 questionnaire achieves perfect sensitivity and specificity in diagnosing the condition within this high-risk population, suggesting its utility for prioritizing care in low-resource settings.

Geoffrey Tabu, Justine Namwagala, Rym Hidour, Hellen T. Aanyu, Ivan Kimuli2026-06-28
📄 medicine

Opioid prescribing practices for dyspnea across palliative care settings: a retrospective observational study

This retrospective observational study at a French university hospital reveals that opioid prescribing practices for dyspnea in palliative care are characterized by substantial variability across different settings, with most patients already on opioids prior to specialist involvement and dose adjustments primarily driven by the need for symptom relief.

Amandine Mathé, Anne-Lise Giffard, Véronique Averous, Camille Saussac, Etienne Rivière, Anais Braverman2026-06-28
📄 medicine

Micronutrient Intake and Dietary Patterns Associated with Cardiometabolic Health Outcomes of Overweight and Obese Pregnant Women in Dodoma, Tanzania

This study in Dodoma, Tanzania, reveals that overweight and obese pregnant women, despite consuming diets linked to both improved hemoglobin and increased cardiometabolic risks, frequently fail to meet micronutrient recommendations and neglect essential supplements.

Jacktan J Ruhighira, Alexander M Tungu, Costantine C Kamata, Elizabeth A John, Davis Ngarashi, Evangelista Malindisa, Fr (…)2026-06-28
📄 medicine

Time in Range Predicts Mortality in Severe Subarachnoid Hemorrhage: A Retrospective Cohort Study on the Mediating Role of Inflammation

This retrospective cohort study of 1,594 severe subarachnoid hemorrhage patients demonstrates that higher Time in Range (TIR) is an independent, potent protective factor against short- and long-term mortality, an association partially mediated by reduced systemic inflammation and most pronounced in non-septic patients.

Yuhang Hu, Xuemei Xu, Jian Chen, Jing Xu, Li Tang, Kangxing Wang, Xianmin Wang2026-06-28
📄 medicine

Barriers and Facilitators to Child Growth Monitoring and Promotion Service Utilization in Gorkha District, Nepal: A Qualitative Study

This qualitative study conducted in Gorkha District, Nepal, identifies multi-level barriers—including geographical inaccessibility, competing household responsibilities, and health system constraints—as the primary drivers of low Growth Monitoring and Promotion (GMP) service utilization, while highlighting community support and service integration as key facilitators for improving uptake.

Jagat Prasad Upadhyay, Damaru Prasad Paneru, Yam Prasad Sharma, Nava Raj Khadka2026-06-28
📄 medicine

Prevalence Associated Factors and Maternal-Perinatal Outcomes of Teenage Pregnancy in Nigeria: A Secondary Analysis of Maternal and Perinatal Database for Quality, Equity and Dignity Data

This secondary analysis of data from 54 Nigerian tertiary hospitals reveals that teenage pregnancy, which has a national prevalence of 3.5% and is concentrated in the North, is associated with significant socio-demographic disadvantages and significantly increased risks of preeclampsia/eclampsia and adverse perinatal outcomes compared to non-teenage pregnancies.

Aisha Abdurrahman, Adewale Olufemi Ashimi, Lawal Ibrahim Magaji, Hadiza Shehu Galadanci, Jamilu Tukur, Hasheem Ibrahim (…)2026-06-28