6901 papers
This study demonstrates that Ganoderic acid A alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting ferroptosis through the upregulation of NLRP3, which subsequently activates the Nrf2/GPX4/SLC7A11 signaling pathway.
This retrospective cohort study of 169 patients found that while both navigation-assisted and robotic-assisted total knee arthroplasty reduced early movement-related pain compared to conventional techniques, robotic-assisted surgery demonstrated the lowest cumulative pain burden from 24 to 72 hours postoperatively.
This study proposes and validates a 3D-printed supramesocolic laparoscopic simulator for choledochoduodenostomy, demonstrating that repeated practice on the model significantly improves surgical skills and reduces procedure time.
This multi-sectoral surveillance study in Burkina Faso reveals a high and varied prevalence of ESBL-producing *Escherichia coli* across human, animal, and environmental sectors, with blood culture isolates showing the highest antibiotic resistance, thereby underscoring the urgent need for enhanced hygiene, integrated surveillance, and rational antibiotic use under the One Health approach.
This multicenter study of 397 pediatric patients in Türkiye characterizes the clinical spectrum of influenza-associated neurological complications, finding that seizures are the most common manifestation with high recovery rates, and validates the Neuroinfluenza Severity Score (NISS) as a highly accurate tool for predicting poor outcomes and guiding early risk stratification.
This paper presents a reproducible workflow for constructing clinically labeled photoplethysmography (PPG) datasets from MIMIC-III, yielding distinct coronary artery disease (CAD) and broader cardiovascular disease (CVD) cohorts with quality-screened waveforms and patient-level clinical annotations to support future cardiovascular research.
This retrospective study of 90 Guinean men with advanced prostate cancer identifies a high ISUP score (≥3) as the sole independent predictor of developing castration resistance, underscoring the critical need for early histological diagnosis and prognostic stratification in this population.
This study of 97 patients at Marmara University found that orthognathic surgery yields high overall satisfaction (94.8%) and functional improvements for both Class II and Class III deformities, with outcomes largely independent of sociodemographic factors except for education's impact on speech satisfaction.
This study successfully translated and culturally adapted the Gait Outcomes Assessment List for Children with Lower-Limb Difference (GOAL-LD™) into German, demonstrating its excellent internal consistency and readiness for use in clinical practice and research to assess health-related quality of life in German-speaking children with lower-limb differences.
This longitudinal study of Shanghai from 2009 to 2024 reveals that while healthcare resource expansion has successfully improved population-based allocation equity, it has simultaneously exacerbated spatial and intra-district inequalities while reducing overall efficiency due to technological regression and urban-suburban structural mismatches, necessitating a strategic shift from scale-driven growth to quality-oriented development.