📄 medicine

COVID-19 Pandemic Changes Epidemiology, Clinical Features and Laboratory Markers of Epstein-Barr Virus Infection in Children: A Three-Period Retrospective Study of 438 Cases

This retrospective study of 438 hospitalized Chinese children reveals that the COVID-19 pandemic significantly altered the epidemiology, clinical severity, and laboratory profiles of Epstein-Barr virus infections, shifting the pattern from primary infections during strict containment to increased viral reactivation and severe complications in the post-pandemic period.

Zheng Zhang¹⁺,, Tao Zhan²⁺,, Jiahui Hu2026-06-26
📄 medicine

Beyond Ventilation: The Non-linear Impact of Per Capita Spatial Volume on Nosocomial Respiratory Virus Transmission in Hospital Wards — A Real-World Natural Experiment

This real-world natural experiment demonstrates that, even with identical mechanical ventilation systems, a 52% reduction in per capita spatial volume in hospital wards is associated with a six-fold increase in nosocomial SARS-CoV-2 transmission, establishing per capita volume as a critical, non-linear determinant of infection risk that warrants equal consideration with air exchange rates in hospital design standards.

Ji-Young Rhee, Si Hyeon Han, Young Kyoung Lee2026-06-26
📄 medicine

AI Benefits and Machine Learning Errors - Neurology, Psychiatry and Neurosurgery

This systematic review of 79 studies (2018–2026) highlights that while AI significantly enhances neurology, psychiatry, and neurosurgery through improved diagnostics and surgical precision, it also introduces substantial risks of misdiagnosis and bias—particularly in underrepresented populations and edge cases—necessitating strict error tracking, fairness audits, and human oversight to ensure safe clinical implementation.

Saif M. Hassan2026-06-26
📄 medicine

Phytochemical-Based Protection Against Benzene-Triggered Leukemic Injury Through Hematologic Recovery, Tissue Preservation, and Nrf2/Caspase-3 Modulation in Rats

This study demonstrates that treatment with *Withania somnifera*, either alone or in combination with green tea extract and curcumin, effectively mitigates benzene-induced leukemic injury in rats by restoring hematological parameters, preserving tissue architecture, and modulating Nrf2 and Caspase-3 expression, with the combination therapy showing superior efficacy in addressing oxidative stress and apoptosis.

Nedim çakır2026-06-26
📄 medicine

Post-Landing Orthostatic Intolerance after Spaceflight: Characterization of Intravenous Fluid Resuscitation in NASA Astronauts

A retrospective review of 79 NASA astronauts reveals that post-landing orthostatic intolerance is frequently treated with highly variable, non-standardized intravenous fluid volumes lacking evidence-based guidelines, highlighting an urgent need for physiology-informed protocols for future deep-space missions.

Lydia Johnson Kolaparambil Varghese, Josef Pleticha2026-06-26
📄 medicine

The Quantified Epidemic Energy (QEE) Model: A Stochastic Framework for Climate- Sensitive Cholera Forecasting in Yemen

This study introduces the Quantified Epidemic Energy (QEE) model, a novel stochastic framework that integrates climate risk and reporting delays to accurately forecast cholera incidence in Yemen's Al-Hodeidah Governorate, offering a robust, uncertainty-quantified tool for proactive early-warning systems in data-scarce, conflict-affected settings.

Hussein Bakery Hussein Dedy, Ali Bannawi ALZubaidy2026-06-26✓ Author reviewed
📄 medicine

Regenerative Treatment of Liver Cirrhosis Using Allogeneic Adipose-Derived Mesenchymal Stem Cells: A Case Report

This case report demonstrates that intravenous infusion of allogeneic adipose-derived mesenchymal stem cells is a safe and effective intervention that significantly improved clinical symptoms, normalized liver enzymes, and halted disease progression in a 69-year-old patient with end-stage liver cirrhosis, offering a promising alternative to liver transplantation.

Sivakumar Allur Subramanian, Deven Patel2026-06-26
📄 medicine

Predictors of Malignancy in Isolated Mammographic Microcalcifications: A Retrospective Cohort Study of Patients Undergoing Stereotactic Biopsy

This retrospective cohort study of 173 patients undergoing stereotactic biopsy for suspicious mammographic microcalcifications found that malignancy was present in 21.4% of cases and identified regional and linear distribution patterns, along with pleomorphic morphology, as independent predictors of malignancy.

Merve Gül Kasım, Eyüp Can İşlek, Berkcan Demirel, Nedim Aykurt, Seçil Gündoğdu, Hakan Ataş2026-06-26
📄 medicine

Development and external validation of an AI pipeline for fully automated DMFT determination from panoramic radiographs

This study presents a deep-learning pipeline that achieves fully automated DMFT determination from panoramic radiographs with overall agreement comparable to that between human dentists, demonstrating strong performance for identifying missing and filled teeth while highlighting persistent challenges in detecting decayed teeth due to the limitations of panoramic imaging.

Babak Saravi, Veronika Shavlokhova, Ashraf Türky, Daman Deep Singh, Felix Schrader, Andreas Vollmer, Norbert Kübler, Chr (…)2026-06-26
📄 medicine

Urinary metabolomic signatures of muscle injury and recovery in elite football players

This longitudinal study demonstrates that urinary metabolomics can identify a specific metabolic signature associated with muscle injury and recovery in elite football players, offering a promising non-invasive tool to complement external load monitoring for individualized athlete assessment.

Guillermo Quintas, Ricard Pruna, Manuel Wong, Sandra Mecho, Pau Madrero, Juan Daniel Sanjuan-Herráez, Gil Rodas2026-06-26