📄 medicine

Intensive community-based exposure with response prevention for children and adolescents with severe and complex obsessive-compulsive disorder

This study demonstrates that an intensive, 8-week community-based CBT-ERP program is an effective alternative to hospitalization for treating children and adolescents with severe and complex obsessive-compulsive disorder, resulting in significant symptom reduction, improved family functioning, and zero hospitalizations during and immediately after treatment.

Katelyn M Dyason, Lara J Farrell, Patrick Pham, Seona Wilson, Sophie M Champion, Jessica R Grisham, Iain E Perkes2026-06-24
📄 medicine

Parkinson’s disease: Individual placebo responses are predicted by baseline expression of a striato-limbic network

This study identifies a specific striato-limbic brain network pattern, characterized by fiber tract density between the nucleus accumbens and anterior cingulate cortex, as a baseline biomarker that predicts individual placebo responses in Parkinson's disease clinical trials.

János Barbero, An Vo, Joshua J. Strohl, Sebastiano Vacca, Chris C. Tang, Nha Nguyen, Prashin Unadkat, Yilong Ma, Shichun (…)2026-06-24
📄 medicine

Visual Management of Nursing Schedules for Workforce Balancing and Reduction of Overtime Coverage: A Longitudinal Quality Improvement Study

This longitudinal quality improvement study demonstrates that implementing a visual workforce management system in a Brazilian tertiary hospital was associated with substantial reductions (over 80%) in nursing overtime coverage events and related costs, despite sustained hospital occupancy and absenteeism.

Raimundo Nonato Diniz Rodrigues Filho, Maria Cláudia Piccolo Barbosa, Gabriela Fernanda Silva Miranda, Lidia Guimarães M (…)2026-06-24
📄 medicine

Prenatal Diagnosis of Unilateral Multicystic Dysplastic Kidney in a Monochorionic Diamniotic Twin Pregnancy: Implications for Vascular Etiology, Counseling and Perinatal Management.

This case report describes a monochorionic diamniotic twin pregnancy with unilateral multicystic dysplastic kidney in one twin, supporting a vascular disruption etiology due to shared placentation while highlighting that the condition carries a favorable prognosis provided the contralateral kidney is normal and amniotic fluid is preserved, necessitating careful surveillance for twin-twin transfusion syndrome and growth discordance.

Arnold Itemba, Anthony Ngowi, Justine Rutagengwa, Hyasinta Jaka, Barbara Mujuma, Edwin Liwa2026-06-24
📄 medicine

Physical activity interventions to support health and wellbeing in healthcare workers: A rapid umbrella review

This rapid umbrella review of 59 reviews and 325 primary studies finds that physical activity interventions generally support the mental and physical health of healthcare workers, though future research must address gaps in cost-effectiveness analysis, cultural adaptation, and study quality to better inform policy.

Joel Owen, Charlotte Edwardson, Emily Oliver, Danielle Lamb, Jake Bodycot, Charles Goss, Padmasayee Papineni, Katherine (…)2026-06-24
📄 medicine

The Effect of Education Provided to Patients Undergoing Planned Percutaneous Coronary Intervention on Self-Efficacy and Secondary Prevention

This single-blind randomized controlled trial demonstrates that a structured education program based on Social Cognitive Learning Theory, delivered to patients undergoing elective percutaneous coronary intervention, significantly improves their knowledge, self-efficacy, healthy lifestyle behaviors, and clinical outcomes compared to standard care.

SENEM KUŞELİ DOST, HÜLYA KAYA2026-06-24
📄 medicine

Antibacterial activities of Parinari Macrophylla Seed Extracts against Salmonella Typhimurium Infection (Gastro-Enteritis) Induced in Wistar Rats.

This study demonstrates that the hydro-ethanolic seed extract of *Parinari macrophylla* exhibits significant antibacterial activity against *Salmonella Typhimurium*-induced gastroenteritis in Wistar rats, effectively reducing fecal bacterial load and showing safety profiles comparable to ciprofloxacin.

JAMES A. NDAKO, Bunmi I.Ajisafe, Stephen O. Owa, Gregory U. Joseph, Shammah I. Ayodele, Akinyomade O. Owolabi, Stephen K (…)2026-06-24
📄 medicine

Assessment of the knowledge, attitudes and practice towards voluntary blood donation among students of College of Health and Medical Technology/Shekhan

This cross-sectional study of 415 students at the College of Health and Medical Technology/Shekhan reveals a significant disparity between adequate blood donation knowledge (54.9%) and actual donation practice (7.95%), highlighting an untapped potential among willing students that requires curriculum revisions and continuous education to bridge.

Sawer Sabri Ahmed2026-06-24
📄 medicine

Safety Precautions and Occupational Exposure to Systemic Anticancer Therapy (SACT): A Qualitative Study

This qualitative study at Sri Lanka's National Cancer Institute reveals that while pharmacists demonstrate high compliance with safety protocols, nurses face the greatest occupational risks and adverse health effects from systemic anticancer therapy due to barriers like work pressure and insufficient protection, highlighting an urgent need for role-specific training and improved safety infrastructure.

Nanayakkara Senarath Appuhamilage Samanthi Nisansala Senarath, Meegoda Kankanange Dona Lalitha Meegoda, Sudath Shirley P (…)2026-06-24