6901 papers
This study successfully developed and characterized an Origanum vulgare leaf oil self-nanoemulsion system that demonstrated superior antimicrobial, anticancer, and anti-inflammatory activities compared to the original oil, highlighting its potential as an effective pharmacological dosage form.
This study demonstrates that in emerging economy public hospitals, institutional digital maturity significantly enhances patient safety culture, clinical quality, and workforce competency, with organizational learning capacity serving as a critical mediator and moderator in this process.
In a cross-sectional study of 252 older adults with depression in a Nigerian tertiary hospital, researchers found that low self-esteem affects 40.5% of patients, with depression severity identified as the strongest predictor and polygamous family structure as a protective factor.
This cross-sectional study of middle-aged and elderly adults found that higher neutrophil-to-lymphocyte ratio (NLR) and systemic inflammation response index (SIRI) are independently associated with carotid plaque, whereas the monocyte-to-high-density lipoprotein cholesterol ratio (MHR) showed no significant association.
A study of 409 Jordanian patients reveals a significant preference for dental practitioners to wear scrubs and personal protective equipment over formal attire or lab coats, with cultural values also influencing a specific preference for female dentists wearing headscarves.
A cross-sectional study of Nigerian doctors reveals that despite varying levels of awareness, primary prevention practices for rheumatic heart disease—specifically throat examinations, diagnostic testing, and appropriate antibiotic duration for streptococcal pharyngitis—are suboptimal among both paediatricians and junior doctors.
This study demonstrates that a machine learning model based on gradient boosting trees, utilizing hemodynamic parameters such as MAP, SVV, VIS, and ELWI to calculate a Vascular Response Index (VRI), effectively predicts 28-day mortality and prognosis in septic shock patients, particularly identifying a critical threshold of VRI < 28.2 associated with significantly higher mortality.
This study demonstrates that a non-invasive scoring index (moya-ASPECTS) derived from slab MIP images in 3D TOF MRA provides a reliable, repeatable method for evaluating postoperative cortical angiogenesis and cerebral blood flow improvement in pediatric Moyamoya disease, offering a practical alternative to invasive procedures for long-term follow-up.
This study of 183 prostate cancer patients undergoing radical prostatectomy identifies pathological ISUP grade 5 as the strongest independent predictor of biochemical recurrence, significantly outperforming other clinicopathological factors in risk stratification.
This study integrates network pharmacology and metabolomics to systematically elucidate that ginsenosides mitigate postoperative hyperfibrinolysis following total hip arthroplasty by modulating multiple targets, such as AKT1 and PTGS2, and key pathways including arachidonic acid metabolism and the complement and coagulation cascades.