📄 medicine

Thyroid Differentiation Score Discordance in BRAF-like Papillary Thyroid Carcinoma: Clinicopathologic Associations and Progression-Free Interval in TCGA-THCA

This study reveals that approximately 30% of BRAF-like papillary thyroid carcinomas retain higher thyroid differentiation scores (TDS), a discordant subgroup characterized by distinct molecular features and a trend toward improved progression-free interval, suggesting that TDS may provide valuable prognostic refinement within this molecular subtype.

David Z. Allen, Kai N. Kelly, J. Walker Rosenthal, Alex Harbison, Joshua J. Kain, Ron J. Karni, Kunal Jain, Jonathon O. (…)2026-06-24
📄 medicine

Barriers to Early Antenatal Care and Its Effect on Malaria Prevention During Pregnancy in the Volta Regional Hospital

This study reveals that despite high knowledge levels regarding antenatal care and malaria prevention among pregnant women in the Hohoe Municipality, early ANC attendance remains low due to significant socio-economic and service delivery barriers, ultimately compromising the effectiveness of malaria prevention strategies.

Richard Awuah, Reina Mrayeba Addo, Livingstone Asem2026-06-24
📄 medicine

Promotora-delivered education to improve Metabolic Dysfunction-Associated Steatotic Liver Disease knowledge and engagement in noninvasive liver assessment in populations at risk for liver cancer: A mixed-methods study

While a promotora-delivered educational intervention significantly improved MASLD knowledge among Latino/Hispanic adults at risk for liver cancer, it did not translate into higher completion rates for noninvasive liver assessments due to structural barriers and contextual factors that outweighed knowledge gains.

Vanessa N. Torres, Arleth A. Escoto, Iris Y. Guzmán-Ruiz, Nicholas Acuna, Jailene Cruz, Leticia Morales, Paulina Monteon (…)2026-06-24
📄 medicine

Ultrasound-guided psoas compartment block using the intertransverse ligament as a tactile endpoint: a technical refinement – a case series of 25 patients

This case series of 25 patients demonstrates that an ultrasound-guided psoas compartment block utilizing the lumbar intertransverse ligament as a definitive tactile endpoint is a feasible, safe, and reproducible technique that achieves rapid, complete sensory blockade with a high success rate and no major complications.

Meng Xiance, Wang Deli, Huang Guihua2026-06-24
📄 medicine

Integrating Clinical Parameters and Cardiotocograms for Real-Time Alerting

This study demonstrates that a hybrid deep learning model fusing raw cardiotocography signals with engineered features outperforms other architectures for real-time fetal state classification, while revealing that the integration of static clinical parameters yields model-dependent results rather than universal improvements.

Caitlyn Schulz, Veronika Kaaz, Lars Brodowski, Vivien Dütemeyer, Thomas M. Deserno2026-06-24
📄 medicine

Randomized trial, parallel-group to compare effect of low-intensity transcranial magnetic stimulation (Li-TMS) on sleep disorders, inflammation levels, and brain-derived neurotrophic factor in patients with depression

This randomized parallel-group trial involving 39 patients with major depressive disorder found that adding low-intensity transcranial magnetic stimulation (Li-TMS) to conventional drug therapy significantly improved depressive symptoms, sleep quality, and specific inflammatory markers compared to sham treatment, although it did not significantly alter BDNF levels.

Blanca Murillo Ortiz, Samanta Medinilla Orozco, Lázaro Ledesma Dueñas, Joel Ramírez Emiliano, Víctor Hugo Bello Lemus2026-06-24
📄 medicine

A Comparative Study on Prediction of Postoperative Acute Heart Failure in Patients with Gynecologic Malignancies under Small-Sample Constraints

This study proposes a robust machine learning framework combining multi-source feature selection and gradient boosting to effectively predict postoperative acute heart failure in gynecologic malignancy patients, addressing the challenges of small-sample and imbalanced clinical data.

Xiaoling Zhang, Hao Xiao, Weibao Jia, Jianing Zhang, Yuan Wang, Baopu Lv, Dongqi Yao2026-06-24
📄 medicine

Severe Exogenous Cushing’s Syndrome with Femoral Avascular Necrosis and Pulmonary Embolism Following Use of an Unregulated “Herbal” Weight-Gain Powder: A Case Report

This case report describes a 27-year-old man who developed severe exogenous Cushing's syndrome, femoral avascular necrosis, and pulmonary embolism after consuming an unregulated "herbal" weight-gain powder adulterated with potent glucocorticoids, highlighting the critical need for greater regulatory oversight and public awareness regarding hidden steroid exposure in unverified supplements.

Fatemeh Sarv, Nasrin Asgari Soran, Haleh Chehrehgosha, Hossein Samadanifard, Amir Ziaee, Mohammad Hossein Teymoori2026-06-24
📄 medicine

Analysis of the current status and influencing factors of cognitive frailty among community-dwelling older adults with olfactory impairment: a cross-sectional study

This cross-sectional study of 419 community-dwelling older adults with olfactory impairment in Changchun City reveals that 24.34% suffer from cognitive frailty, which is independently driven by unmarried status, sarcopenia, nutritional risk, and oral frailty, highlighting the need for targeted screening and interventions.

Liu Jie, Ma Shuang, Li Jian, Zhang Jingzhou, Hou Yiting2026-06-24