6901 papers
This comparative cross-sectional study conducted in Nigeria demonstrates that Periodontal Inflamed Surface Area (PISA) is a highly accurate and independent predictor for distinguishing moderate-to-severe periodontitis from periodontal health, supporting its potential utility as a diagnostic biomarker in both clinical practice and research.
This propensity score-matched study demonstrates that using 8-Fr catheters for percutaneous transhepatic gallbladder drainage results in significantly fewer adverse events and higher clinical success rates compared to 6-Fr catheters in patients with acute calculous cholecystitis.
This pilot study demonstrates that biochemical assessment of vitamin D status is feasible and acceptable among pregnant women in Dodoma, Tanzania, revealing a 31.7% prevalence of suboptimal levels despite abundant sunlight exposure and highlighting the need for larger studies to confirm these findings.
This study characterizes immune-related liver injury (irLI) as comprising two distinct subtypes—transient acute injury in normal livers and persistent immunologic flares on pre-existing chronic liver disease—distinguished by onset kinetics, metabolic risk factors, and histological features, thereby providing a framework for personalized management in patients treated with immune checkpoint inhibitors.
This prospective multicenter study found a significant positive correlation between perceived alarm and overall workload in Swedish emergency departments, identifying that the proportion of ambulance arrivals and the frequency of technical alarms independently contribute to increased alarm workload beyond general staffing demands.
This large-scale evaluation of over 280,000 ClinicalTrials.gov records reveals that while registry-reported Data Monitoring Committee (DMC) use increases with trial risk, a significant structural gap persists, with the majority of high-risk trials lacking reported DMC oversight.
This case report describes a rare instance of maxillary sinus fungal infection causing ptosis and diplopia in a 73-year-old female, highlighting the importance of considering this etiology in atypical ocular presentations through imaging and pathological confirmation.
This study utilizing data from 1,105 elderly rural hypertensive patients in China reveals that specific unhealthy lifestyle factors, including prolonged sedentary behavior, poor sleep quality, and the consumption of animal oil and ultra-processed foods, significantly negatively impact health-related quality of life, while increased moderate physical activity and better sleep management enhance it.
This study demonstrates that narcolepsy type 1 is characterized by specific subregional brain volume alterations in frontal, temporal, and subcortical areas that correlate with the patients' cognitive deficits, affective disturbances, and sleep-related symptoms.
This longitudinal study of 4,497 Chinese adults demonstrates that higher baseline non-exercise estimated cardiorespiratory fitness is independently associated with a significantly reduced risk of progressive frailty, establishing it as a key, interpretable predictor for early identification and prevention in community and primary care settings.