6901 papers
This prospective observational study demonstrates that the propofol effect-site concentration at loss of consciousness strongly predicts the concentration required to achieve a BIS of 50 for intubation, enabling the derivation of a practical dosing formula to guide monitor-independent target-controlled infusion induction.
This cross-sectional study of over 3,000 physical and occupational therapists in São Paulo, Brazil, reveals a predominantly young, female, and highly educated workforce committed to professional development, yet facing significant challenges in income equity, workplace safety, and geographic distribution that necessitate targeted policy reforms.
This bibliometric analysis of 1,983 publications from 2005 to 2025 maps the global evolution of glioma and hypoxia research, highlighting a paradigm shift from basic molecular mechanisms to translational frontiers driven by the tumor immune microenvironment, epigenetic lactylation, and emerging technologies like AI-assisted radiomics and nanomedicine.
This study developed and validated the DEPACS model, an explainable machine learning tool using routine health checkup data to effectively screen for depression in older adults living alone without relying on specific mental health assessments.
This case report documents the first instance of disseminated *Mycobacterium sherrisii* infection in an Indian HIV-positive patient, highlighting the critical need for rapid molecular identification and targeted macrolide-based therapy to distinguish it from tuberculosis and manage immune reconstitution inflammatory syndrome.
This study concludes that while smartphone-based thermal cameras (Infiray P2 Pro and T3 Pro) exhibit lower image-quality fidelity than high-end research-grade devices, their strong agreement in thermal pattern recognition makes them a viable, cost-effective, and patient-friendly alternative for routine thermographic monitoring in physiotherapy.
This retrospective before-and-after cohort study demonstrates that a modified percutaneous pedicle screw placement technique significantly reduces the incidence of immediate severe postoperative pain and facet joint violations in patients undergoing fixation for thoracolumbar fractures compared to the conventional method.
This cross-sectional study demonstrates that integrating diastolic morning surge, T-peak–to–T-end interval, and neutrophil-to-lymphocyte ratio significantly improves the discriminatory accuracy for identifying echocardiographically defined left ventricular diastolic dysfunction beyond standard clinical and ambulatory blood pressure parameters.
This prospective comparative study demonstrates that serum calprotectin exhibits superior diagnostic accuracy for acute appendicitis compared to conventional markers like WBC, CRP, and the Alvarado score, while also serving as a potential indicator of disease severity.
This cross-sectional study utilizing CHARLS data developed and validated an explainable Random Forest machine learning model that effectively stratifies cardiovascular disease risk in middle-aged and older adults with diabetes using eight key clinical variables.