medicine papers | Gist.Science

Twenty-One Years of Colorectal Malignancies at a Palestinian Pathology Network: A Retrospective Analysis of 1,381 Cases (2005–2026)

This retrospective analysis of 1,381 colorectal malignancy cases from a Palestinian pathology network (2005–2026) reveals a rising incidence with a notably high burden of early-onset disease, a balanced sex ratio, and a predominance of left-sided adenocarcinomas, highlighting the urgent need for expanded registries and revised screening guidelines in the region.

Ibrahim Salhi, Husni Maqboul, Firas Jallad, Hani Jaradat, Sami Bannoura, Duaa El-Krunz, Bashar Karmi, Zaidoun Salah2026-06-24

📄 medicine

Recurrent anterior capsule contraction after femtosecond laser-assisted cataract surgery in a patient with Eales disease: a case report

This case report describes a rare instance of recurrent anterior capsule contraction syndrome following femtosecond laser-assisted cataract surgery in a patient with Eales disease, highlighting the role of chronic inflammation and surgical factors in its pathogenesis and demonstrating the efficacy of repeated Nd:YAG laser capsulotomies in managing the condition.

Yan Li, Na Li, Kaifang Wang, Mingchao Qiao, Xiaocong Fan2026-06-24

📄 medicine

Water Exchange Improves Patient Acceptability During Unsedated Esophagogastroduodenoscopy: A Randomized Controlled Trial

This randomized controlled trial demonstrates that while water exchange during unsedated esophagogastroduodenoscopy provides only a modest reduction in patient discomfort, it significantly improves overall procedural acceptability, satisfaction, and willingness to undergo repeat examinations compared to traditional air insufflation.

Yen-Chun Chen, Chih-Wei Tseng, Yu-Hsi Hsieh2026-06-24

📄 medicine

Integrating Creative and Community Health Services into Clinical Workstreams: A Qualitative Case Study from Gloucestershire Integrated Care Board

This qualitative case study of Gloucestershire Integrated Care Board reveals that the long-term integration of Creative Health into statutory clinical workstreams over 25 years was driven by the co-evolution of data infrastructure, commissioning alignment, and relational trust, yet remains vulnerable to funding cycles and the tensions of institutional conformity.

Jane Hearst, Helen J. Chatterjee, Felicity Penn, Hannah Gorf2026-06-24

📄 medicine

Social and intersectional inequalities in the occurrence of food insecurity in Southern Brazil after the pandemic: who are the most affected?

A 2022/23 cross-sectional study in Southern Brazil reveals that food insecurity affects 34.1% of adults and elderly, with a cumulative risk approximately three times higher for women of color with low education due to the intersectional impact of gender, race, and socioeconomic status.

Rosália Garcia Neves, Thaynã Ramos Flores, Suele Manjourany Silva Duro, Nicolly dos Santos Gonçales, Taciéli Gomes Lacer (…)2026-06-24

📄 medicine

KCNJ2 p.Val93Ile-related cardiac channelopathy with a hypertrophic cardiomyopathy- like phenotype: a case report

This case report describes a 70-year-old Chinese man with a KCNJ2 p.Val93Ile variant who presented with an atypical cardiac channelopathy featuring a hypertrophic cardiomyopathy-like phenotype and ventricular arrhythmias, suggesting a potential expansion of the KCNJ2-related disease spectrum while acknowledging that a definitive causal link to structural cardiomyopathy remains unproven.

Lixia Zhou, Sai Ye, Yue Su, Qizhi Jin, Anyi Fu, Yang Yang, Jiao Wang2026-06-24

📄 medicine

Trends and Determinants of Tramadol Consumption in Chile: Evidence From National Health Surveys (2003–2017)

This study analyzes Chilean National Health Surveys from 2003 to 2017 and reveals a dramatic 19-fold increase in tramadol consumption, which disproportionately affects older adults, women, and individuals with osteoarthritis or depression, highlighting the urgent need for targeted opioid stewardship and integrated pain management strategies.

Fernando R. Altermatt, Javiera Leniz, Paula León, Alvaro Passi-Solar, Paula Margozzini2026-06-24

📄 medicine

Time-Dependent Evaluation of Genotoxic Effects Following CBCT Exposure in Pediatric Patients Using Buccal Micronucleus Assay

This study demonstrates that cone-beam computed tomography (CBCT) exposure induces significant, temporary genotoxic effects in pediatric patients, as evidenced by a peak increase in buccal micronucleus frequency at 15 days post-scan followed by partial recovery at 30 days, underscoring the necessity of strict radiation protection protocols.

Shivani Dhonde, Pallavi Channe, Pravin Matole, Sheetal Ubhale, Trupti Gaikawad2026-06-24

📄 medicine

Autism Detection based on Structural MRI using YOLO

This study proposes a novel diagnostic framework for Autism Spectrum Disorder that leverages YOLO deep learning models on preprocessed 2D sMRI slices to achieve superior accuracy and efficiency compared to traditional architectures, offering a promising tool for early clinical detection and personalized intervention.

Emad Alsukhni, Enas Alikhashashneh, Suha Rababah2026-06-24

📄 medicine

Anxiety and Depressive Symptoms among Patients with Chronic Obstructive Pulmonary Disease in Syria: A Cross-Sectional Study of Spirometric and Patient-Reported Correlates

This cross-sectional study of 249 Syrian COPD patients reveals a high prevalence of anxiety (30.9%) and depression (73.9%), identifying patient-reported challenge burden as a stronger independent correlate of psychological severity than spirometric impairment, thereby supporting the need for multidimensional care that integrates psychological screening.

Ibrahim Alkhatib, Mohammad Alaa Aldakak, Othman Alawad Almlhem, Lama Alsaoub, Hussam Al-Bardan2026-06-24

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