6901 papers
This 24-month practice-based randomized controlled trial found that selective and complete caries removal in primary molars yield similar clinical outcomes regarding restoration failure and tooth survival, suggesting that operator and case-related factors are more influential on success than the excavation method itself.
This single-center retrospective study demonstrates that anesthesiologists with higher annual volumes of pancreaticoduodenectomy cases are associated with shorter anesthesia times, reduced intraoperative hypotension, distinct multimodal analgesic and fluid management strategies, and fewer severe postoperative complications compared to their low-volume counterparts.
This retrospective study demonstrates that embedding a genetic counsellor-led stewardship service within a public health system in Queensland effectively improved genomic testing quality, reduced inappropriate test orders, educated non-genetic clinicians, and generated significant cost savings, thereby proving the model's efficacy and sustainability for scaling genomic medicine in mainstream care.
This retrospective pilot series of three patients demonstrates that da Vinci SP-assisted Davydov vaginoplasty is a feasible and safe surgical approach for treating Mayer–Rokitansky–Küster–Hauser syndrome, yielding favorable early anatomic, functional, and histopathologic outcomes with minimal complications.
This prospective observational study found that while serum copeptin levels correlate with hemorrhagic shock severity and transfusion needs in trauma patients, they lack independent predictive value for advanced shock after adjusting for injury severity and other clinical parameters, suggesting a potential role as an adjunctive rather than standalone diagnostic biomarker.
This study presents a robust methodology for utilizing UK electronic health records to construct a retrospective cohort of 83,283 women with incident diabetes, successfully distinguishing those with a background of gestational diabetes from those without to facilitate future research on long-term complications.
This cross-sectional study of Chinese college students reveals that approximately one-quarter have excess body weight, which is independently associated with male sex, infrequent vegetable consumption, and a preference for noodle-based take-out meals.
This process evaluation of the Veggie Van intervention reveals that higher implementation fidelity, particularly regarding nutrition education components, is significantly associated with greater increases in fruit and vegetable consumption among participants in underserved communities, underscoring the critical link between faithful execution and positive dietary outcomes.
This study demonstrates that the leaf extract, alkaloid fraction, and isolated ricinine of *Ricinus communis* effectively suppress DMBA/MPA-induced breast carcinogenesis in rats by restoring mammary tissue architecture and inhibiting tumor progression through the downregulation of TNF-α, PI3K, and STAT3 signaling pathways alongside the modulation of PPARα.
This longitudinal study evaluating Nigeria's Primary Healthcare Under One Roof policy over a decade reveals a statistically significant but uneven national improvement (mean progress of 56.4%), with critical disparities across implementation pillars—particularly in legislation and office setup—necessitating targeted interventions for underperforming states to achieve integrated quality healthcare.