📄 medicine

Preoperative Membranous Urethral Length Predicts Quality-of-Life Recovery and Urinary Incontinence after Holmium Enucleation of the Prostate

This study demonstrates that a longer preoperative membranous urethral length measured on MRI independently predicts better quality-of-life recovery and a lower risk of stress urinary incontinence six months after Holmium laser enucleation of the prostate.

Naoya Nagasaki, Takuya Sadahira, Ichiro Tsuboi, Tomofumi Watanabe, Shin Kanemoto, Yusuke Tominaga, Satoshi Katayama, Shi (…)2026-06-24
📄 medicine

Combinatorial Targeting of Avapritinib-Driven MAP Kinase Activation in High-Grade Glioma

This study reveals that avapritinib treatment in PDGFRA-altered high-grade glioma induces a compensatory MAPK pathway activation that sustains tumor survival, and demonstrates that combining avapritinib with MEK inhibition effectively suppresses this adaptive resistance to produce durable therapeutic benefits.

Carl Koschmann, Kallen Schwark, Kelsey Wink, Antonella De Cola, Madeline Miclea, Tirth Patel, Seongbae Kong, Alina Stanc (…)2026-06-24
📄 medicine

Baseline Neutrophil-Lymphocyte Ratio Combined with Mean Corpuscular Volume in Predicting Catheter-Related Bloodstream Infection: A Retrospective Case-Control Study

This retrospective case-control study demonstrates that combining baseline elevated neutrophil-lymphocyte ratio (NLR) and decreased mean corpuscular volume (MCV) significantly improves the prediction of central line-associated bloodstream infections (CLABSI), offering a valuable tool for early risk stratification and targeted prevention.

Xiurong Song, Junjun Wu, Lingxia Shi, Shuna Huang, Ke Ma, Fan Yang, Liyun Lin, Qiaoxian Zhang2026-06-24
📄 medicine

Risk of Cutaneous Melanoma Among Haematological Malignancy Survivors: A Population-Based Analysis Using Large-Scale Queensland Cancer Registry Data

This population-based study of Queensland cancer registry data reveals that while haematological malignancy survivors do not face a statistically significant overall excess risk of cutaneous melanoma, they exhibit marked subtype-specific variations with elevated risks particularly among males, those aged 50–79, and individuals with specific lymphoid subtypes, supporting the need for risk-stratified skin surveillance.

Ashmitha Kumar, Arunan Jeyakamar, Alfred King-yin Lam, Vinod Gopalan2026-06-24
📄 medicine

Artificial Intelligence as Supplementary Learning Tool in Pharmacology Tutorials: Students’ Perceptions and Knowledge Outcomes 

This quasi-experimental study involving 69 preclinical medical students in Malaysia found that while AI tools like ChatGPT were positively perceived as effective supplementary resources for clarifying concepts and saving time in pharmacology tutorials, they did not produce measurable knowledge gains, likely due to high baseline performance, suggesting they should be integrated cautiously with faculty oversight.

Kay Zar Hla Win, Anjan Khadka, Tray Zar Hla Win2026-06-24
📄 medicine

CT-Based Radiological Score (AMESI CT-Score) for Severity of Bowel Injury in Acute Mesenteric Ischemia

This study introduces the AMESI CT-Score, a radiological tool based on specific CT signs that demonstrates moderate accuracy in predicting irreversible bowel injury in arterial occlusive acute mesenteric ischemia to aid clinical triage, while noting that the absence of these signs does not rule out necrosis.

MARTIN REIM, Merli Koitmäe, Miklosh Bala, Alan Biloslavo, Dumitru Casian, Andee Dzulkarnaen Zakaria, Hanne Fuglseth, Mor (…)2026-06-24
📄 medicine

Image-only ultrasound AI for dating-independent delivery-date prediction externally validated in four Chilean hospitals

This study demonstrates that an image-only artificial intelligence system, validated across four Chilean hospitals, accurately predicts delivery dates with a mean absolute error of 6.9 days and significantly outperforms conventional dating methods—particularly for late-presenting pregnancies lacking reliable early gestational data—by eliminating the need for biometric or demographic inputs.

Rodrigo Alliende-Ferrada, Ignacia Inostroza, Jocelyn Stern, Cristobal Pérez-Cotapos, Andrés Ruz2026-06-24
📄 medicine

Co-design, implementation and evaluation of an SMS health messaging program in a very remote Aboriginal community in Australia

Through a co-design approach involving community leadership and cultural relevance, an SMS health messaging program was successfully implemented and evaluated in a very remote Aboriginal community, demonstrating high acceptability, technical feasibility, and utility for health promotion.

Josielli Comachio, Nicki Newton, Vishnu Khanal, Emily Saurman, Amy Von Huben, Clara Chow, Nadarajah Kangaharan, Josie Po (…)2026-06-24