📄 medicine

Effect of time interval between Neoadjuvant Chemoradiation and Esophagectomy surgery on pathological complete response of patients with Esophageal Cancer

This retrospective study of 147 esophageal cancer patients found that while a longer interval between neoadjuvant chemoradiation and esophagectomy was associated with a consistent, non-significant trend toward higher pathological complete response rates, the results do not definitively confirm the benefit of delaying surgery and warrant further investigation through prospective trials.

Fereidoon Amanat Yazdi, Fatemeh Moosaie, Nima Taghizadeh Mortezaei, Soha Mohammadi, Seyede Marzie Fatemi Abhari, Ali Moo (…)2026-06-24
📄 medicine

Association Between Sampaio Pelvicalyceal System Anatomy and Surgical Outcomes in Retrograde Intrarenal Surgery

This retrospective study of 128 patients undergoing retrograde intrarenal surgery suggests that Sampaio pelvicalyceal system anatomy influences surgical outcomes, with subtype B2 independently associated with significantly higher stone-free rates compared to subtype A1.

Tuncer Bahceci, Mustafa Tıpırdamaz, Ozan Aydogan, Burak Güler, Cagatay Ozsoy, Akif Erbin, Umut Alkan, Mustafa Gok, Alpar (…)2026-06-24
📄 medicine

Clinical and Laboratory Profile in Different Types of Primary Immune Deficiency Disorders (PIDs) in Children: A BMU Perspective

This study characterizes the clinical and laboratory profiles of children with primary immune deficiency disorders (PIDs) at BMU, revealing that antibody deficiencies and syndromic combined immunodeficiencies are the most common types among confirmed cases, while highlighting a significant diagnostic delay that underscores the urgent need for increased physician awareness and early referral to improve patient outcomes.

Mohammad Imnul Islam¹, Kamrul Laila², Ismet Nigar³, Hafiz Al-Mamun⁴, Mujammel Haque⁵, Mohammed Mahbubul Islam⁶, Manik Ku (…)2026-06-24
📄 medicine

Diagnostic Concordance of mpMRI and Ga68 PSMA PET/CT on Localization of Prostatic Lesions in Patients with Suspected Prostate Cancer and Negative TRUS-Guided Biopsy

This study demonstrates that in patients with rising PSA levels and prior negative biopsies, the combined interpretation of mpMRI and Ga68 PSMA PET/CT achieves high diagnostic concordance with histopathology, significantly improving the localization and detection of clinically significant prostate cancer.

Abhishek Choube, Shushant Shandilya, Amrut Phonde, Prashant Kumar Rai, Sushant Trakroo, Nishan Gaudani2026-06-24
📄 medicine

Quality and reliability of Chinese short-form health information about hypertension and type 2 diabetes on TikTok: a comparative cross-sectional study

This comparative cross-sectional study of 300 Chinese TikTok videos reveals that health information on hypertension and type 2 diabetes is generally of low quality, with medical professionals producing significantly better content than individual users and platform popularity proving to be an unreliable indicator of information reliability.

Xingwang Qiu, Xia Luo, Xiaotao Xu, Shanmei Zhou, Shixuan Yuan, Jin Zhang, Hua Guan2026-06-24
📄 medicine

Efficacy of makhana (Euryale ferox Salisb) flatbread (roti) as a dinner-substitution medical nutrition therapy in adults with type 2 diabetes mellitus: a randomised controlled trial

This randomized controlled trial demonstrates that substituting dinner with makhana-based roti significantly improves glycemic control, reduces insulin secretory demand, and decreases waist circumference in adults with type 2 diabetes compared to rice roti or usual diet, suggesting it as a culturally appropriate dietary adjunct for diabetes management.

Mahesh Kumar Mummadi, Vishwakarma RK, Samarasimha Reddy, RajenderRao Kalashikam, Jha SN, Makhana Group2026-06-24
📄 medicine

Osmotic demyelination syndrome in severe hyponatremia: independent association with sodium correction rates when accounting for established risk factors.

In a large retrospective cohort study of adults with severe hyponatremia, baseline risk factors such as extremely low initial sodium levels, hypokalemia, and alcohol abuse were found to be significantly more predictive of osmotic demyelination syndrome than the rate of sodium correction, challenging the assumption that marginal differences in correction speed are the primary determinant of this complication.

Dustin Mark, Mubarika Alavi, Mary E Reed2026-06-24
📄 medicine

The Weight of Progress: A Sequential Mediation Analysis of Socioeconomic Drivers, the Nutrition Transition, and the Hypertension Epidemic in Nepal

Using data from the 2019 Nepal WHO STEPS Survey, this study reveals that socioeconomic factors drive hypertension in Nepal primarily through indirect pathways mediated by obesity and stress, highlighting the critical role of the nutrition transition and psychosocial factors in the country's rising cardiometabolic disease burden.

Biraj Neupane, Niharika Jha, Bikram Adhikari, Silon Pant, Jyoti Badu, Ian Brooks, Csaba Varga2026-06-24