📄 medicine

Validating Acute Coronary Syndrome ICD Codes as Training Labels for Clinical AI

This 10-year retrospective study of nearly 620,000 emergency department encounters validates that while ICD-coded Acute Coronary Syndrome labels exhibit high sensitivity and specificity, their moderate positive predictive value is driven by systematic, interpretable errors—primarily suspected cases later ruled out or coder omissions—making them suitable training labels for AI screening models where missing a diagnosis is more critical than over-identification.

Daniel K. Amponsah, Gabrielle Bunney, Kate Miller, Ariadna Garcia, Anna Graber-Naidich, Keejeong Ryu, Himani Darji, Mari (…)2026-10-19
📄 medicine

Dietary behaviors, diet quality and nutritional status of motorcycle taxi (zémidjan) drivers in Cotonou, Benin: a cross-sectional study

This cross-sectional study of 253 motorcycle taxi drivers in Cotonou, Benin, reveals a coexisting double burden of underweight and overweight driven by a poorly diversified, carbohydrate-dominant diet, with low dietary diversity linked to underweight and alcohol consumption associated with overweight.

Colette Sylvie Azandjème, Folachadé Ibidoun Rodiath Bankole, Gbemahon Roger Houssou, Schadrac Gbaguidi, Clémence Metonno (…)2026-10-19
📄 medicine

Five-Year Longitudinal Changes and Determinants of Serum PFAS Exposure Profiles in a Community-Based Cohort from Southern China

This five-year longitudinal study of 958 Guangzhou residents reveals heterogeneous trends in serum legacy PFAS levels, characterized by decreases in most compounds but a notable increase in PFOA, with exposure patterns significantly influenced by age and residential location.

Heng Zhao, Yan Wu, Yuling Chen, Wenru Feng, Jie Shi, Chuangwei Weng, Wenjing Liang, Yongcong Deng, Li Bu, Tianji Lin, Si (…)2026-10-19
📄 medicine

Prevalence and Risk Factors of Child Sexual Abuse in Early Childhood Across Africa: A Protocol for a Systematic Review and Meta-Analysis

This protocol outlines a systematic review and meta-analysis designed to synthesize evidence on the prevalence and risk factors of child sexual abuse among children aged 8 years and younger across Africa, aiming to address critical knowledge gaps and inform targeted prevention policies and child protection systems.

Hawa Abdillah, Xiangmin Tan, Anne Nyambura Njogu, Nan Hua, Yi Zeng, Yuqing He, Siyuan Tang, Mei Sun, Maritta Välimäki2026-10-19
📄 medicine

Femtosecond laser ablation of dental restorative materials toward digitally enabled precision dentistry

This study demonstrates that femtosecond laser ablation offers a precise, digitally controlled alternative to conventional rotary instruments for removing dental restorations by establishing quantitative processing windows, confirming superior surface quality with minimal thermal damage, and validating its feasibility for cavity preparation and removal in human teeth.

Jade (Peiyu) Yuan, Ksenia Maximova, Peter Woodfield, Andrei V. Rode, Laurence J. Walsh, Heiko Spallek, Omar Zuaiter, Ste (…)2026-10-19
📄 medicine

Exploring pain management training needs of community nurses: a qualitative study

This qualitative study of 12 community nurses in Nanchang identifies five key themes regarding their pain management training needs, emphasizing the necessity for a systematic, practice-oriented programme that integrates clinical decision-making, flexible interactive methods, and organizational support to bridge the gap between theoretical knowledge and real-world community practice.

Xiaoxiong Sun, Xiaoang Zhang, Weichen Liu, Daying Zhang, Andi Zhou, Xinyu Ou, Yanhong Ma, Jianmei Wei2026-10-19
📄 medicine

Associations Between Dietary Patterns, Lifestyle Factors, and Metabolic Syndrome Components in a Ghanaian Cohort at Baseline of Freeze-Dried Beta Vulgaris (Beetroot) Powder Intervention Study

This baseline cross-sectional study of 214 Ghanaian adults reveals a high prevalence of metabolic syndrome components, significant gender disparities, and distinct dietary patterns characterized by excessive sodium and inadequate calcium intake, underscoring the urgent need for culturally tailored interventions to address metabolic risks in this transitioning population.

Elizabeth Boatemaa, Christopher Larbie, Marina Tandoh, Herman Erick Lutterodt, Michael Asante Fosu2026-10-19
📄 medicine

Promoting Psychosocial Well-being among Women with Polycystic Ovary Syndrome through Emotional Intelligence Training: A Randomized Controlled Trial

This randomized controlled trial demonstrates that a four-week emotional intelligence training program significantly improves emotional intelligence, marital satisfaction, and health-related quality of life among married women with Polycystic Ovary Syndrome, with benefits sustained over a three-month follow-up period.

Heba M. Mohamed, Mervat Aly khamis, Ghada Hassan Ahmed, Mohammed Ibrahim Touni Ibrahim, A. F Abdelkawi, Asmaa Abo Bakr H (…)2026-10-19
📄 medicine

Basal Ganglia Iron Accumulation Mediates Stage-Dependent Associations Between Plasma pTau217 and Hippocampal Atrophy in Alzheimer’s Disease

This study demonstrates that basal ganglia iron accumulation acts as a stage-dependent mediator linking plasma pTau217 to hippocampal atrophy in Alzheimer's disease, with the strongest iron-mediated effects observed during the prodromal stage.

Pengbo Gao, Haoye Tan, Guangshi Li, Jinxia Liang, Mingfeng Yang, Danyan Xu, Qiang Wang, Shuang Liang, Zhidai Xiao, Xiaom (…)2026-10-19
📄 medicine

Prevalence and Population Burden of Cardiovascular–Kidney–Metabolic Syndrome Stages Among Mexican Adults: A Nationally Representative Cross-Sectional Study

This nationally representative cross-sectional study of Mexican adults reveals that nearly 90% of the population meets criteria for Cardiovascular–Kidney–Metabolic (CKM) syndrome, with the majority concentrated in Stage 2 and a significant burden already evident in early adulthood, highlighting an urgent need for integrated prevention strategies.

Rubén Silva-Tinoco, Alejandro Avalos-Bracho, Alinne A. Rivas-Alarcón, Aldo Ferreira-Hermosillo, Daniel Elías-López, Hugo (…)2026-10-19