📄 medicine

Implementation Fidelity and Quality of the Community Health Information System at Primary Health Care Level in Rural Ethiopia: A Historical Process Evaluation of the 2016 CHIS Implementation

This historical process evaluation of the 2016 Community Health Information System (CHIS) implementation in rural Ethiopia found that while the system achieved a "very good" overall performance score with strong resource availability and household registration, it faced significant challenges in data consistency and routine updating that require targeted improvements in supervision and training.

Mesaud Mohammedbirhan Adem, Kiros Demoz, Taddele Weldeslassie Awalom, Mengistu Hagazi Tequar, Tesfay Gebregzabher2026-10-19
📄 medicine

Co-Designing a Social Prescribing Intervention for Carer-Employees: A Qualitative Exploration of Stakeholder Perspectives

This qualitative study explores the lived experiences and needs of carer-employees through stakeholder interviews and a co-design workshop to inform the development of a scalable social prescribing intervention aimed at improving caregiver well-being and sustaining workforce participation in Canada.

Allison Williams, Reemal Shahbaz, Zeest Kadri, Brooke Chmiel, Sarah Neil-Sztramko, Kate Mulligan, Winny Fung2026-10-19
📄 medicine

Electroacupuncture at Shenting (GV24) and Baihui (GV20) Alleviates Cognitive Impairment in MCAO/R Rats by Inhibiting cGAS–STING Signaling Pathway–Associated Ferroptosis

This study demonstrates that electroacupuncture at Shenting (GV24) and Baihui (GV20) alleviates post-stroke cognitive impairment in MCAO/R rats by inhibiting the cGAS-STING signaling pathway, thereby suppressing ferroptosis.

Jun Chen, Yamin Wang, Yujie Zhang, Yaqi Luo, Kewen Ma, Xinbao Tian, Zhaochun Wang, Tao Hu, Jing Gao, Xiaodong Feng2026-10-19
📄 medicine

Beyond biological threats: A global ecological study of International Health Regulations (2005) core capacities and multi-hazard disaster outcomes, 2015–2023

This global ecological study demonstrates that stronger International Health Regulations (2005) core capacities, particularly in laboratory, coordination, surveillance, and risk communication, are significantly associated with reduced mortality and morbidity from multi-hazard disasters, thereby validating the framework's relevance beyond biological threats.

Thein Than Htay -, Feng-Jen Tsai2026-10-19
📄 medicine

Delayed graft function and outcome-data readiness after pediatric kidney transplantation in Ecuador: a single-center retrospective cohort

This single-center retrospective study of 62 pediatric kidney transplants in Ecuador highlights a 12.3% delayed graft function rate and significant data completeness gaps, underscoring the urgent need for standardized minimum datasets to enable reliable longitudinal outcome analysis in settings with limited registry infrastructure.

Santiago Alejandro Chávez Fuenmayor, Frances Johanna Fuenmayor Oramas, Junior Rafael Gahona Villegas, Rosa Alba Quiguant (…)2026-10-19
📄 medicine

Prenatal phenotypes and outcomes of left-sided and duplicated inferior vena cava according to hepatic IVC continuity: a retrospective cohort study

This retrospective cohort study of 167 fetuses with left-sided or duplicated inferior vena cava reveals that while the interrupted hepatic IVC pattern (Type B) is strongly associated with complex cardiac anomalies and left isomerism, the drainage pattern itself does not independently predict fetal death, though it necessitates comprehensive prenatal assessment.

Bin Ma^, Yanfang Wang^, Lan Bu^, Fang Nie2026-10-19
📄 medicine

Rafiq: An Arabic Conversational AI System for Early Depression Detection with Integrated Symptom Monitoring, PHQ-9 Screening, and Retrieval-Augmented Generation

This paper introduces Rafiq, a clinically validated Arabic conversational AI system that integrates a curated mental health knowledge base, a 217-expression PHQ-9 lexicon for symptom detection, and a retrieval-augmented generation pipeline to enable early depression screening and psychoeducation for Arabic-speaking communities.

Alaa Alshurafa, Basem Alijla, Motaz K H SAAD2026-10-19
📄 medicine

Possible Neurosarcoidosis Presenting with Chronic Pachymeningeal Disease, Extensive Cerebral Venous Sinus Thrombosis, and Recurrent Seizures: A Case Report

This case report describes a 42-year-old woman with a 12-year history of progressive neurological decline and extensive cerebral venous thrombosis, initially misdiagnosed as tuberculous meningitis, who was ultimately treated for possible neurosarcoidosis with corticosteroids and methotrexate, resulting in significant clinical improvement despite the lack of definitive histological confirmation.

Kinfemicheal Tilahu Yigzaw2026-10-19
📄 medicine

Induced Abortion and Incident Asthma in Chinese Women: A Prospective Cohort Study with Insights from Baseline Peak Expiratory Flow Measurements

This prospective cohort study of Chinese women found that a history of induced abortion, but not spontaneous pregnancy loss, is independently associated with an increased risk of incident asthma, while also revealing that parity and menopausal timing correlate with objective lung function measures despite self-reported COPD diagnoses showing systematic access bias.

JiaPing Lu, Heng Xu, Qiulian Xu2026-10-19