552 papers
Microbiology explores the invisible world of tiny life forms that shape our health, environment, and even the air we breathe. From bacteria and viruses to fungi and parasites, this field investigates how these microscopic organisms interact with us and each other, driving everything from disease outbreaks to beneficial fermentation processes. Understanding them is crucial for developing new medicines, improving food safety, and combating global health challenges.
At Gist.Science, we make the latest discoveries in this dynamic field accessible to everyone. We process every new preprint uploaded to bioRxiv in this category, transforming dense academic findings into both clear, plain-language explanations and detailed technical summaries. This ensures that whether you are a student, a researcher, or simply curious, you can grasp the significance of cutting-edge science without getting lost in jargon.
Below are the most recent papers in microbiology, curated and summarized directly from the bioRxiv server to keep you at the forefront of discovery.
This study reveals that glutamyl-endopeptidases (GEPs) produced not only by the pathogen *Staphylococcus aureus* but also by commensal species like *Staphylococcus epidermidis* and *Staphylococcus capitis* can cleave PAR1 to induce itch signaling and disrupt skin barrier integrity, suggesting a broader microbial basis for atopic dermatitis symptoms than previously recognized.
This study establishes a Syrian hamster model demonstrating that SARS-CoV-2 can persist in multiple tissues for up to one year without productive replication, driving organ-specific immune and metabolic alterations that may underlie long-term post-acute sequelae.
This study demonstrates that Aedes anphevirus, Guadeloupe mosquito virus, and verdadero virus persist in long-term laboratory colonies of *Aedes aegypti* through highly efficient biparental vertical transmission, suggesting their potential as candidates for gene delivery in mosquito vector control strategies.
This study demonstrates that bovine-derived H5N1 influenza virus can efficiently infect lactating swine via the mammary gland and be transmitted to piglets through milk, causing productive but clinically inapparent infections that pose a significant risk of subclinical spread within commercial swine populations.
This study introduces and characterizes an engineered *E. coli* BL21 (DE3) strain lacking endogenous SodFMs, which serves as an effective host for producing high-purity, metal-specific recombinant superoxide dismutase isozymes for detailed biochemical and structural analysis.
This study demonstrates that recombinant dimeric Platelet Factor 4 (rdPF4) acts as a cationic opsonin that binds to the negatively charged capsule of *Klebsiella pneumoniae*, thereby enhancing CR3-mediated phagocytosis and significantly improving bacterial clearance and survival in a mouse sepsis model.
This study reveals that in *Streptococcus pneumoniae*, the non-cognate sensor kinase VncS promotes host cell adhesion by cross-phosphorylating and activating the response regulator RR06 to upregulate the adhesin CbpA, a process normally restrained by the cognate kinase HK06 acting as a phosphatase.
This study demonstrates that seed-applied multi-kingdom synthetic communities can effectively colonize *Brassica napus* seedlings and reshape native microbiota, revealing that selecting ecologically relevant strains with specific traits like high seed abundance and low lag-time is more critical for success than the specific assembly strategy used.
Using a *Caenorhabditis elegans* model, this study demonstrates that treating *Pseudomonas aeruginosa* PA14 infections with specific bacteriophages does not alter the composition of the native gut microbiome, supporting the safety of phage therapy regarding microbiome disruption.
In corn monoculture soils, the retention of plant residue selectively enriches antagonistic phenotypes among lignin-degrading *Streptomyces* due to competition for lignin breakdown products, whereas non-degrading isolates show no such treatment-dependent shift in antagonism.