1968 papers
This study demonstrates that while color offers no advantage for object recognition in clear images, it provides a significant benefit when spatial information is degraded by blur, suggesting that the evolutionary development of human trichromacy may have been driven by the need to compensate for optical degradation associated with aging and light exposure.
This study reveals that atypical alpha oscillatory activity in autistic children and their siblings is primarily characterized by reduced temporal stability and density of alpha bursts rather than diminished oscillatory amplitude, suggesting that the instability of these rhythms serves as a neural marker for altered cortical excitability and sensory regulation.
This study demonstrates that the cost-efficient [2,3,4,6,6-2H5]glucose produces comparable HDO levels to [2H7]glucose in both in vitro and in vivo settings, establishing it as a viable, lower-cost alternative for 2H-based metabolic imaging.
This study identifies WDR44 as a critical adaptor protein that drives the initiation of de novo α-synuclein aggregation at the lysosomal membrane in Parkinson's disease, thereby compromising lysosomal function and promoting neuronal dysfunction, which positions the WDR44–α-synuclein interaction as a promising therapeutic target for early intervention.
This study reveals that in pediatric stroke, systemic inflammation drives neutrophil infiltration through the meningeal barrier via IL-36γ signaling, establishing the meninges as a critical staging site for immune-mediated brain injury and identifying IL-36γ blockade as a promising therapeutic strategy.
This paper presents an optimized protocol for isolating high-quality, myelin-free nuclei from mouse hippocampus and cerebellum using benchtop gradient centrifugation and optional magnetic enrichment, enabling successful single-nucleus RNA sequencing.
Using brainstem-optimized fMRI, this study demonstrates that task-dependent modulation of stretch-evoked motor responses is associated with measurable, instruction-specific activation changes in human brainstem reticulospinal regions, confirming their role in rapid feedback control.
This paper presents a fully automated method that integrates T1-weighted, T2-FLAIR, and T2-weighted MRI contrasts to achieve self-consistent tissue segmentation and robust identification of perivascular spaces, validated on 773 datasets from 403 participants in aging and Alzheimer's disease studies.
This study demonstrates that visual mechanisms alone, specifically static masking and the naturalistic temporal structure of saccadic velocity profiles, significantly reduce perceived motion during simulated eye movements, thereby supporting perceptual continuity across saccades.
This study demonstrates that the human visual cortex follows a retinotopic wiring principle where cortical regions representing the same visual locations preferentially connect, a structural organization that preserves neural geometry and explains perceptual asymmetries across the human lifespan.