1296 papers
Neuroscience explores the intricate machinery of the brain and nervous system, seeking to understand how we think, feel, and move. From the microscopic dance of individual neurons to the complex networks that shape our memories and behaviors, this field peels back the layers of our biological selves to reveal the origins of consciousness and disease.
At Gist.Science, we bring these discoveries directly from bioRxiv, the leading preprint server for biological sciences, to a broader audience. We process every new neuroscience preprint as it is uploaded, transforming dense academic manuscripts into clear, plain-language explanations alongside detailed technical summaries. This ensures that both curious readers and specialists can stay current with the latest breakthroughs before they are formally published.
Below are the latest neuroscience papers we have processed from bioRxiv, offering fresh insights into the workings of the mind.
This study demonstrates that reciprocal repulsion between inversely expressed cell-surface proteins Teneurin-m and Capricious drives the segregation of dendrites into discrete spatial domains within the Drosophila olfactory circuit.
This study establishes a comprehensive, open-access normative database of TMS-EEG metrics derived from 164 healthy adults, characterizing the reliability and redundancy of 968 features to enable validated individual-level cortical excitability and connectivity assessments.
This study demonstrates that predictive pursuit in high-dimensional recurrent neural networks emerges through the development of internal target predictions and egocentric representations, requiring sufficient network rank to support allocentric coding and aligning with observed rodent behavior.
By using longitudinal mesoscopic calcium imaging in mice following bilateral enucleation, this study reveals that adult cortical plasticity occurs through two distinct, overlapping temporal windows characterized by spatially dissociated changes in activity patterns and network structure.
The paper argues that the previously reported mismatch between BOLD signals and oxygen metabolism is primarily driven by high statistical uncertainty and noise in metabolic estimates rather than actual physiological reversals.
This study demonstrates that a mismatch between spontaneous neural activity and glymphatic clearance, which is transcriptionally linked to synaptic function, serves as a comprehensive mechanism driving regional amyloid-β deposition and neurodegeneration in the human cortex.
This study demonstrates that precise high-density theta burst stimulation of the rat medial prefrontal cortex prevents the incubation of cocaine craving and restores functional connectivity, providing a mechanistic foundation for translating targeted TMS as a therapeutic intervention for cocaine use disorder.
By training mice on visual discrimination tasks and recording up to 73,000 neurons across multiple visual areas, researchers demonstrated that neural representations of novel stimuli in medial higher-order visual areas, but not primary areas, specifically correlate with behavioral generalization and require prior visual experience.
This study demonstrates that timing-dependent long-term depression (tLTD) between layer 5 pyramidal cells in the visual cortex critically depends on astrocytic calcium signaling and the activation of astrocyte CB1 receptors, revealing a fundamental role for astrocytes in regulating spike timing-dependent plasticity.
This study proposes and validates a computational model suggesting that the primary function of continual learning in the resource-constrained insect brain is to facilitate forgetting, thereby enabling the acquisition of new information while minimizing the negative impacts of memory loss.