1296 papers
Neuroscience explores the intricate machinery of the brain and nervous system, seeking to understand how we think, feel, and move. From the microscopic dance of individual neurons to the complex networks that shape our memories and behaviors, this field peels back the layers of our biological selves to reveal the origins of consciousness and disease.
At Gist.Science, we bring these discoveries directly from bioRxiv, the leading preprint server for biological sciences, to a broader audience. We process every new neuroscience preprint as it is uploaded, transforming dense academic manuscripts into clear, plain-language explanations alongside detailed technical summaries. This ensures that both curious readers and specialists can stay current with the latest breakthroughs before they are formally published.
Below are the latest neuroscience papers we have processed from bioRxiv, offering fresh insights into the workings of the mind.
This study reveals that astrocytic α7nAChRs, rather than neuronal ones, are essential for cognitive function and the efficacy of related therapeutics by regulating D-serine levels to modulate NMDAR signaling.
This study demonstrates that pre-stimulus EEG activity contains single-trial, modality-specific predictive templates for both cued and uncued trials, which are linked to shifts in decision-making strategies and confirm that expectations can form even without explicit cues.
This study demonstrates that the auxiliary subunit ABHD6 accelerates the desensitization and deactivation of TARP γ-2-containing AMPA receptors, thereby regulating their gating kinetics in a TARP γ-2-dependent manner.
This paper introduces the Signal Generating (SiGn) fMRI phantom, a 3D-printed, anthropomorphic device that mimics dynamic brain activity through a hemin-based infusion system, enabling rigorous, end-to-end quality assurance of fMRI pipelines by providing a known ground-truth signal that can be processed through standard human data workflows.
This study demonstrates that magnetophosphene perception induced by suprathreshold 20 Hz magnetic field stimulation is characterized by spatially distributed, broadband gamma-band EEG activity rather than focal low-frequency oscillations, challenging classical assumptions about visual processing markers.
Using high-resolution 3D imaging, this study reveals that during tangential loading, approximately 70% of fingertip skin deformation occurs in out-of-contact peripheral regions and propagates inward, exhibiting directional asymmetries and localized wrinkling patterns that are critical for advancing biomechanical models and understanding tactile neural encoding.
This study establishes a novel single-cell transcriptomic resource for canine dorsal root ganglion neurons using deep FLASH-seq, revealing conserved sensory neuron subtypes, species-specific expression patterns of pain and itch receptors, and potential evolutionary influences of domestication to advance comparative translational neuroscience.
This study reveals that in the substantia nigra pars reticulata, dopamine suppresses tonic GABAergic inhibition through a dual mechanism involving direct GABA release from dopaminergic neurons and D2 receptor-mediated modulation of astrocytic GABA uptake, thereby regulating motor behavior.
This study demonstrates that the thalamic lateral posterior (LP)/pulvinar-to-anterior cingulate cortex (ACC) pathway is essential for integrating prior stimulus history to guide decision-making by encoding evidence differences along a curved, low-dimensional neural manifold.
This study demonstrates that fine-scale exogenous attention within the high-acuity foveola selectively enhances contrast sensitivity for low-to-mid spatial frequencies (4–8 CPD) while leaving higher frequencies unaffected, indicating that this involuntary mechanism remains inflexible and frequency-specific even at the center of vision.