Role of GABA and NMDA receptors in shaping cortical timescales and large-scale network dynamics
By pharmacologically manipulating neurotransmitter receptors in healthy participants and analyzing resting-state MEG data, this study provides causal evidence that GABAergic inhibition, rather than NMDA receptor activity, regulates cortical timescales and large-scale network dynamics, thereby linking microscale synaptic mechanisms to the brain's temporal organization and cognitive function.