👁️ Category

ophthalmology

36 papers

Association of axial length and changes in aqueous depth with refractive outcomes in Chinese primary angle closure glaucoma patients

This study demonstrates that in Chinese primary angle closure glaucoma patients undergoing phacoemulsification, axial length and the pre- to post-surgical change in aqueous depth are significantly associated with intraocular lens power calculation errors, suggesting that accurately predicting these changes is crucial for optimizing refractive outcomes, particularly in acute cases with an axial length of 22 mm or greater.

Wang, L., Yang, Y., Ng, T. K. + 2 more2026-04-14👁️ ophthalmology

Three-dimensional topography of Descemet's membrane in Fuchs endothelial corneal dystrophy using laser scanning confocal microscopy and white-light interferometry

This study demonstrates that combining white-light interferometry and laser scanning confocal microscopy enables label-free, high-resolution three-dimensional topographic characterization of Descemet's membrane in Fuchs endothelial corneal dystrophy, revealing significantly increased surface roughness and distinct spatial zones of guttae compared to healthy controls.

Maurin, C., Poinard, S., Travers, G. + 7 more2026-04-08👁️ ophthalmology

Impact of Socioeconomic Status on Clinical Features and Outcomes of Bacterial Keratitis: The Midlands Infectious Keratitis Study

This retrospective multicentre study of 320 patients in the UK found that socioeconomic deprivation does not significantly influence the clinical presentation or outcomes of bacterial keratitis, suggesting that universal access to emergency ophthalmic care may attenuate potential disparities in this sight-threatening condition.

Javed, K. M. A. A., Ozturk, B., Anwar, S. + 6 more2026-04-07👁️ ophthalmology

Long-term impact of Training the Trainers program on Primary Eye Care networks in Malawi using the Arclight Project package

A three-year follow-up study in Malawi reveals that while the Arclight Project's "Training the Trainers" model successfully established vertical mentorship networks and empowered Health Surveillance Assistants as community eye focal points, the long-term sustainability of these primary eye care networks requires intentional strategies to strengthen informal horizontal peer connections beyond mere skills transfer.

Windle, T., Maliko, F., Burgiss-Kasthala, S. + 1 more2026-04-02👁️ ophthalmology

Paving the way for automated transscleral cyclophotocoagulation: predicting ciliary body arc length from biometric data using a two-sphere eye model

This study introduces a biometric-based two-sphere eye model demonstrating that ciliary body arc length varies significantly among individuals, thereby challenging the standard 22 mm treatment assumption and highlighting the necessity of personalized calculations to ensure accurate fluence delivery in transscleral cyclophotocoagulation.

Szabo, A., Arpadffy-Lovas, T., Toth-Molnar, E.2026-03-31👁️ ophthalmology

Epidemiology and Associated Risk Factors of Diabetic Retinopathy in Patients with Diabetes Mellitus Attending a Tertiary-care Hospital in Hargeisa, Somaliland

This hospital-based cross-sectional study in Hargeisa, Somaliland, reveals a high 51% prevalence of diabetic retinopathy among diabetes patients, identifying age over 40, longer disease duration, marital and employment status, literacy, and concomitant cardiac illness as significant risk factors, thereby underscoring the urgent need for enhanced health policies and regular eye screening in the region.

Woredekal, A. T.2026-03-31👁️ ophthalmology

How 'Micro' is Microperimetry? - Characterizing the Effect of Fundus Tracking on the Psychometric Function

This study demonstrates that while fundus tracking in microperimetry primarily improves psychometric precision by reducing false positives and sharpening sensitivity curves at non-seeing retinal loci, it supports a defensible suprathreshold criterion intensity of 10 to 13 dB for distinguishing seeing from non-seeing retina.

Lipsky, T., Ehrenzeller, C., Ansari, G. + 4 more2026-03-27👁️ ophthalmology

Whole-genome sequence genome-wide association study in All of Us identifies a novel glaucoma risk locus in African ancestry individuals

This study leverages whole-genome sequencing data from the diverse All of Us cohort to identify a novel glaucoma risk locus near *CYP2A7* specifically in African ancestry individuals, demonstrating the critical value of genetic diversity and refined phenotypic definitions in uncovering new genetic insights for primary open-angle glaucoma.

Aboobakar, I. F., Cruz, L. A., Kinzy, T. G. + 16 more2026-03-22👁️ ophthalmology

Multi-omics liquid biopsy identifies mitochondrial dysfunction in geographic atrophy and supports the longevity-associated metabolite alpha-ketoglutarate as a therapeutic strategy

This study utilizes multi-omics liquid biopsy to identify mitochondrial dysfunction as a hallmark of geographic atrophy and demonstrates that oral alpha-ketoglutarate supplementation can effectively modulate intraocular metabolites to potentially restore energy metabolism.

Yeh, T.-C., Velez, G., Prasad, A. + 14 more2026-03-19👁️ ophthalmology

Safety and Effectiveness of Iota-Carrageenan Eye Drops for the Treatment of Dry Eye Disease

This prospective clinical investigation demonstrates that four weeks of treatment with iota-carrageenan eye drops is safe, well-tolerated, and effective in significantly alleviating symptoms, stabilizing the tear film, and protecting the ocular surface in patients with mild-to-moderate dry eye disease, even under adverse environmental conditions.

Blanco Vazquez, M., Calonge, M., Dellago, H. + 4 more2026-03-18👁️ ophthalmology

Evolving Ocular Safety Signals of EGFR Inhibitors: A FAERS Disproportionality Analysis of Amivantamab, Mobocertinib, and Classic Agents

This study utilizes a FAERS disproportionality analysis to confirm a strong, class-wide signal of ocular toxicity ranging from benign eyelash abnormalities to sight-threatening complications across both classic and newer EGFR inhibitors, underscoring the critical need for proactive ophthalmologic monitoring in patients receiving these therapies.

Khan, Z. S., Nadel, A., Joly, T. J.2026-03-18👁️ ophthalmology