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Cystatin-C versus Creatinine-Based eGFR in Bardet-Biedl Syndrome: Implications for Chronic Kidney Disease Detection

This study demonstrates that in pediatric patients with Bardet-Biedl syndrome, cystatin-C-based eGFR identifies significantly more cases of chronic kidney disease than creatinine-based estimates, particularly in females, suggesting that routine reliance on serum creatinine alone may underestimate kidney impairment in this population.

Kalliopi Vardaki, Elizabeth Forsythe, Asheeta Gupta, Kathryn Sparks, Philip Beales, Faidra Veligratli2026-07-27
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Robotic Assisted Versus Conventional Total Knee Arthroplasty: Meta-analysis

This meta-analysis of twelve studies indicates that while robotic-assisted total knee arthroplasty offers superior radiographic alignment, greater postoperative range of motion, and better functional scores compared to conventional manual techniques, it requires longer operative time and does not consistently improve all patient-reported outcomes.

I Gusti Ngurah Wien Aryana, I Wayan Suryanto Dusak, Cokorda Gde Oka Dharmayuda, Gusti Ngurah Putra Stanu, Febyan Febyan (…)2026-07-27
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Evaluation and Management of Clinically Significant Arrhythmias in the Early Neonatal Period

This retrospective study of 40 neonates demonstrates that early diagnosis and appropriate medical management of clinically significant arrhythmias, particularly supraventricular tachycardia and non-conducted premature atrial contractions, lead to favorable outcomes with low recurrence and mortality rates, even in cases complicated by arrhythmia-induced cardiomyopathy.

Taner Kasar, Emine Yurdakul Ertürk2026-07-27
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Controlled Time-Series Proxy for Waterflooding Optimization

This paper presents a rigorously validated engineering workflow that integrates Bayesian optimization, genetic algorithms, and NPV-aware regularization to transform LSTM-based time-series proxies into reliable decision-support tools for waterflooding optimization, demonstrating that predictive accuracy alone is insufficient to guarantee economic returns and emphasizing the necessity of high-fidelity simulator re-evaluation.

Alexandre de Souza Junior, Juan A. R. Tueros, Leonardo C. Oliveira, Silvana M. B. Afonso, Bernardo Horowitz2026-07-27
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Adaptive Graph Construction and Feature-Enhanced Graph Neural Network for Few-Shot Bearing Fault Diagnosis under Variable Conditions

This paper proposes AG-MS-GNN, a novel few-shot bearing fault diagnosis framework that integrates adaptive physical graph construction, negative-sample-free contrastive feature enhancement, and multi-scale graph attention to achieve high-accuracy, generalizable diagnosis under variable operating conditions with limited data.

Zhi Sun, Xiaoyu Deng, Chunlin Zhang, Yibo Luo, Jinglei Zhao2026-07-27
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Unmanaged plastic waste significantly increases dengue burden

This study introduces a material-specific extension of the WHO-recommended Breteau Index using Sri Lankan surveillance data to demonstrate that unmanaged plastic waste serves as a major breeding habitat, accounting for approximately 22–34% of the national dengue burden and providing a practical framework for linking waste management policies to infectious disease control.

Prasad Liyanage, Sakunthala Janaki, Anoja Dheerasinghe, Preshila Samaraweera, Jagath Amarasekera, Sampath Weerakoon, Cos (…)2026-07-27
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Targeting penicillin binding protein 2a in methicillin resistant Staphylococcus aureus using selected phytocompounds: an environmental surveillance and in silico molecular docking study

This study detected methicillin-resistant *Staphylococcus aureus* carrying the *mecA* gene in household harvested rainwater in Nigeria and utilized in silico molecular docking to identify epigallocatechin gallate, luteolin, andrographolide, and apigenin as promising phytocompounds for targeting the PBP2a protein, though these findings require further experimental validation.

Benson Okorie, Blessing Awoyemi, Emeka Okorie, Ukamaka Okpor, Tracy Osatohan, Promise Ogungbemi, Akin Oyewumi, Richmore (…)2026-07-27
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Polyphasic characterization reveals the first evidence of an atypical AFG1-dominant toxigenic profile of Aspergillus section Flavi in Uganda's cassava value chain

This study provides the first evidence of an atypical AFG1-dominant toxigenic profile in Aspergillus section Flavi isolates from Uganda's cassava value chain, identifying soil as the primary contamination reservoir and highlighting that relying solely on AFB1 detection may underestimate aflatoxin risks.

Elias Oyesigye, Carla Cervini, Angel Medina, George Mahuku2026-07-27