998 papers
This integrative review reframes AI-mediated clinical decision support as an auditable knowledge-governance system, synthesizing 108 records to highlight gaps in relational autonomy and dignity while presenting tentative, non-confirmatory quantitative signals regarding mortality surveillance and clinician activation.
This randomized crossover study demonstrates that while evaporative cooling garments effectively reduce peripheral skin temperatures in hot-dry environments, a cooling vest alone provides most of the physiological benefits, with combined multi-garment systems offering only marginal additional advantages and limited impact on core temperature or cardiovascular strain.
This prospective exploratory study suggests that daily Tadalafil significantly improves pain, erectile function, urinary symptoms, and quality of life in men with pudendal nerve entrapment and erectile dysfunction, though the findings require confirmation through randomized controlled trials.
This case report details the long-term clinical course of a 9.5-year-old male with MAGIS syndrome caused by a de novo GNAI2 variant, highlighting suboptimal growth response to growth hormone therapy and the progressive development of multiple endocrine deficiencies including prolactin, gonadotropin, and thyroid dysfunction.
This study demonstrates that localized delivery of an IL-2-expressing oncolytic vaccinia virus (vvDD-IL-2-RG) synergizes with PD-1 inhibition to significantly reduce tumor burden and enhance T-cell infiltration in a clinically relevant, de novo rat model of esophageal adenocarcinoma.
This case report describes a rare instance of a young man with previously undiagnosed Behçet disease who presented with the unusual combination of catastrophic multisite thrombosis and pyoderma gangrenosum as initial manifestations, ultimately achieving complete remission through aggressive immunosuppressive therapy.
This case report demonstrates that video-assisted thoracoscopic surgery (VATS) enucleation is a feasible and safe alternative to esophagectomy for giant esophageal gastrointestinal stromal tumors exceeding 9 cm, while highlighting the critical role of CD117 positivity in diagnosis and the potential to avoid adjuvant therapy.
Using ambient-noise tomography on a temporary seismometer network, researchers imaged a shallow, pressurized magma storage zone and an overlying hydrothermal conduit beneath Mt. Aso's Nakadake crater, revealing how these structures facilitate fluid transport and generate volcanic tremors.
This SEER population-based cohort study utilizing covariate-balancing propensity score weighting demonstrates that cytoreductive nephrectomy is independently associated with significantly improved overall and cancer-specific survival in patients with metastatic renal cell carcinoma, particularly those with lower-stage disease.
This registry-based cohort study characterizes the demographic, clinical, functional, and radiological profiles of 148 patients with fibrotic interstitial lung disease at high altitude in Bogotá, Colombia, revealing connective tissue disease as the most common etiology and highlighting a significant association between clinical symptoms and radiological findings that may be influenced by altitude-related physiological adaptations.