📄 other

177Lu-FAP-2286 Radioligand Therapy in End-Stage Metastatic Cancer: a promising theranostic approach

This single-center retrospective study demonstrates that 177Lu-FAP-2286 radioligand therapy is a feasible and relatively safe treatment option for end-stage metastatic cancer patients who have exhausted standard therapies, offering meaningful disease control and survival benefits while highlighting baseline 68Ga-FAP-2286 PET/CT parameters as independent prognostic factors.

Chengzhi Jiang, Dong Huang, Peng Wang, Yanggang Liu, Wenlu Zheng, Yue Chen2026-07-25
📄 other

Radiographic progression at castration-resistant transition in metastatic castration-sensitive prostate cancer: prognostic impact and clinical features

This study demonstrates that radiographic progression at the transition to castration-resistant prostate cancer significantly predicts poorer post-progression survival in real-world metastatic castration-sensitive patients, with lower baseline PSA levels potentially identifying those at higher risk for such progression.

Takeru Fujimoto, Takayuki Sumiyoshi, Kei Mizuno, Takanari Kambe, Toshifumi Takahashi, Hiroshi Fujiwara, Masashi Kubota (…)2026-07-25
📄 other

Pre-pectoral direct-to-implant reconstruction without acellular dermal matrix or synthetic mesh after minimally access (endoscopic or robotic assisted) nipple-sparing mastectomy

This study demonstrates that pre-pectoral direct-to-implant breast reconstruction without acellular dermal matrix or synthetic mesh, performed via minimally invasive nipple-sparing mastectomy, is a feasible approach with an acceptable complication profile and favorable short-term aesthetic outcomes.

Surita Said, Shih Lung Lin, Yi Yuan Lee, Hung Wen Lai2026-07-25✓ Author reviewed
📄 other

A Randomized Open-Label Prospective Study of Remineralizing Therapy for Dental Caries in School-Aged Children

This randomized open-label prospective study demonstrates that fluoride-, calcium-, and arginine-containing products effectively promote enamel remineralization and increase acid resistance in school-aged children with initial dental caries, while highlighting the superior diagnostic and monitoring capabilities of combining quantitative light-induced fluorescence (QLF) with the enamel resistance test (ERT) over traditional visual-tactile methods.

Azizbek Zhabborov, Farida Yakubova, Feruza Makhkamova, Pulat Abilov2026-07-25
📄 other

Effectiveness of a smartphone application (“BP Fit”) for community-based management of hypertension in urban primary care: a quasi-experimental study

This quasi-experimental study in urban India demonstrates that the "BP Fit" smartphone application, when combined with standard care, significantly improves blood pressure control, medication adherence, quality of life, and lifestyle behaviors among hypertensive patients compared to standard care alone over a six-month period.

Ravali A, Sunil Kumar D, Hari Prakash G, Deepika Yadav, Vanishri Arun, Rakesh M, Arun Gopi2026-07-25
📄 other

Directly Measured Hemodynamic Variability Reveals Network Target Engagement During Prefrontal iTBS

By combining interleaved TMS-fMRI with simultaneous fNIRS to directly measure individual hemodynamic variability, this study demonstrates that conventional fMRI models often miss target engagement during prefrontal iTBS, whereas using subject-specific hemodynamic signals reveals significant activation in the left DLPFC and its connected network.

Georg Kranz, Adam Xia, Nancy Shi, Ivan Chak, Alvin Tang, Tim Lin, Sharie Wang, Penny Qin, Minxia Jin, Bella Zhang, Rebec (…)2026-07-25
📄 other

Psychological preparedness for disaster in elementary school students: scale development and a preliminary evaluation of a video-based disaster education program

This study developed and validated a new psychological preparedness scale for Japanese elementary students and demonstrated that a hybrid disaster education program combining immersive video simulation with cognitive behavioral therapy-based psychoeducation significantly increased students' preparedness levels.

Takahiro Kubo, Kensuke Takenouchi, Masahiro Takamoto, Masayuki Suzuki, Kunihiro Nakahara, Chiharu Sadamitsu2026-07-25