959 papers
This study demonstrates a significant nonlinear dose-response relationship between D-dimer levels and venous thromboembolism risk in heart failure patients, characterized by a steep increase at low levels followed by a plateau, which was observed across sexes and specifically in the HFrEF subtype but not in HFpEF.
This 12-year national registry study from Iran characterizes the clinical and immunological features of 23 patients with Chediak–Higashi syndrome, highlighting a significant diagnostic delay, high rates of parental consanguinity, and the critical need for early genetic screening and hematopoietic stem cell transplantation to prevent life-threatening complications.
This study developed and internally validated a practical nomogram using five routinely available clinical and laboratory variables to predict the efficacy of dual antiplatelet therapy in acute ischemic stroke patients, demonstrating moderate discrimination and potential utility for personalizing treatment in resource-limited settings.
This study demonstrates that the Stone Volume–Density Index (SVDI), a composite parameter derived from stone volume and density, is a superior predictor of postoperative treatment failure in percutaneous nephrolithotomy compared to traditional stone metrics, although stone parameters generally lack predictive value for complications.
This 10-year big data analysis of nearly one million emergency department visits reveals that prolonged length of stay is driven by interconnected operational factors—specifically consultation burden, advanced imaging utilization, ED workload, and continuity of care—rather than isolated time-based metrics, suggesting that performance improvements require broader systems-based approaches to address workflow bottlenecks.
This retrospective study of 87 fetuses with congenital renal agenesis demonstrates that integrating chromosomal microarray and whole-exome sequencing significantly improves the detection of pathogenic genetic abnormalities, which are the primary determinants of adverse pregnancy outcomes and the key factor distinguishing between termination for bilateral cases and favorable live births for unilateral cases.
This study demonstrates that sex-specific lateralization of cortical surface area in frontotemporal regions serves as a neural substrate for sex-differential social behaviors in autism, mediated by distinct neurobiological mechanisms involving synaptic function, astrocytes, and specific neurotransmitter systems.
This randomized controlled trial found that a single hypnotic safety intervention with a post-hypnotic anchor did not significantly improve subjective well-being or sleep quality over the following week, though it showed a potential trend toward reducing pre-bedtime heart rate.
This study demonstrates that adopting a toe-out orientation during badminton lunge landing reduces internal knee tissue stress and redistributes load compared to a toe-in orientation, which concentrates stress and increases injury risk.
This study investigates the impact of electronic banking technologies (ATM, mobile, internet, and agent banking) on job security among employees at Commercial Bank of Ethiopia's Hawassa branches, finding that while ATM, mobile, and agent banking negatively affect job security, internet banking has a positive effect, leading to recommendations for adopting employee-friendly technologies.