998 papers
This single-center retrospective study demonstrates that 177Lu-FAP-2286 radioligand therapy is a feasible and relatively safe treatment option for end-stage metastatic cancer patients who have exhausted standard therapies, offering meaningful disease control and survival benefits while highlighting baseline 68Ga-FAP-2286 PET/CT parameters as independent prognostic factors.
This retrospective study of 283 patients demonstrates that robot-assisted pelvic channel screw placement achieves excellent overall accuracy (98.6%), with short screws showing significantly higher precision than trans-cortical screws and a BMI ≥30 kg/m² identified as a key risk factor for malposition.
This study provides in vivo evidence that amyloid-beta pathology drives a longitudinal, spatiotemporally specific decline in mGluR5 availability, particularly in medial temporal regions, which serves as a predictor of future cognitive deterioration in Alzheimer's disease.
This study demonstrates that radiographic progression at the transition to castration-resistant prostate cancer significantly predicts poorer post-progression survival in real-world metastatic castration-sensitive patients, with lower baseline PSA levels potentially identifying those at higher risk for such progression.
This study demonstrates that pre-pectoral direct-to-implant breast reconstruction without acellular dermal matrix or synthetic mesh, performed via minimally invasive nipple-sparing mastectomy, is a feasible approach with an acceptable complication profile and favorable short-term aesthetic outcomes.
This randomized open-label prospective study demonstrates that fluoride-, calcium-, and arginine-containing products effectively promote enamel remineralization and increase acid resistance in school-aged children with initial dental caries, while highlighting the superior diagnostic and monitoring capabilities of combining quantitative light-induced fluorescence (QLF) with the enamel resistance test (ERT) over traditional visual-tactile methods.
This quasi-experimental study in urban India demonstrates that the "BP Fit" smartphone application, when combined with standard care, significantly improves blood pressure control, medication adherence, quality of life, and lifestyle behaviors among hypertensive patients compared to standard care alone over a six-month period.
By combining interleaved TMS-fMRI with simultaneous fNIRS to directly measure individual hemodynamic variability, this study demonstrates that conventional fMRI models often miss target engagement during prefrontal iTBS, whereas using subject-specific hemodynamic signals reveals significant activation in the left DLPFC and its connected network.
This study developed and validated a new psychological preparedness scale for Japanese elementary students and demonstrated that a hybrid disaster education program combining immersive video simulation with cognitive behavioral therapy-based psychoeducation significantly increased students' preparedness levels.
This study demonstrates a significant nonlinear dose-response relationship between D-dimer levels and venous thromboembolism risk in heart failure patients, characterized by a steep increase at low levels followed by a plateau, which was observed across sexes and specifically in the HFrEF subtype but not in HFpEF.