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Penile Doppler Ultrasound Systolic Impairment Predicts Major Cardiovascular Events in poor responders to PDE5-i Therapy

This study demonstrates that impaired penile peak systolic velocity in men with erectile dysfunction refractory to PDE5 inhibitors is independently associated with higher cardiovascular risk and serves as a significant predictor of future major cardiovascular events, suggesting penile Doppler ultrasound is a valuable tool for risk stratification in this population.

Andrea Piasentin, Federico Zorzi, Luca Braulin, Alessandra Sartorel, Serena Sartori, Giulio Rossin, Arianna Biasatti, St (…)2026-07-25
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Interstitial Lung Disease Associated with Immune Checkpoint Inhibitors in Gastrointestinal Cancer Treatment: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System (FAERS) Database and EudraVigilance Database

This pharmacovigilance study analyzing FAERS and EudraVigilance data reveals that immune checkpoint inhibitor-induced interstitial lung disease in gastrointestinal cancer patients exhibits distinct, agent-specific risk profiles regarding gender, onset timing, and geographic variation, underscoring the need for risk-stratified monitoring to mitigate its high fatality rate.

ruiying Chen, Pengkhun Nov, Jiqiang Li2026-07-25
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Rare Horseshoe Venous Confluence of Retroaortic Left Brachiocephalic Vein and Dual-Column Azygos Veins

This paper reports a previously unreported anatomical variation in a 61-year-old male cadaver featuring a horseshoe venous confluence formed by a dual-column azygos system and a retroaortic left brachiocephalic vein, highlighting its critical implications for thoracic imaging, surgical planning, and procedural safety.

Eric B. Lu, Tess A. Korte, Maureen R. Cranley, Joseph Cherullo, Yun Tan, Daniel T. Daly2026-07-25
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Effects of concentrate supplementation on fecal microbiota, serum metabolomics, and proteomics in grazing Yili horses

This study demonstrates that moderate concentrate supplementation in grazing early-lactation Yili horses significantly alters fecal fermentation patterns and microbial composition while regulating serum metabolic and proteomic profiles related to glucose, lipid, and energy metabolism, thereby improving their overall nutritional status.

Mengfei Li, Zihao Xu, Long Sun, Zhiqiang Cheng, Yingying Yu, Lingkai Sun, Mairehaba Aierken, Fengming Li, Changjiang Zan (…)2026-07-24
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Rapid Self-Driven Formation of Conducting Polymers for Bioelectronics.

This paper introduces a rapid, equipment-free, self-driven polymerization method that enables the one-step fabrication of high-performance conducting polymer coatings on diverse metal surfaces, facilitating the creation of multifunctional bioelectronic devices such as glucose biosensors and high-fidelity nerve interface arrays.

Xenofon Strakosas, Rémy Cornuéjols, Tobias Abrahamsson, Venkata Perla, Nader Marzban, Jakob Von Heideken, Donghak Byun (…)2026-07-24
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Age-appropriate Completion and Coverage of Key Childhood Vaccines in Greater Accra, Ghana, 2014–2023

This study analyzing Greater Accra's 2014–2023 immunization data reveals that while overall coverage for children aged 12–23 months improved significantly, age-appropriate completion for infants under 11 months remains suboptimal with substantial district-level disparities and data quality concerns.

Daniel Addotei, Gifty Boateng, Charles Lwanga Noora, Raymond Dankoli, Jocelyn Laryea, Ishmael Kunateh, Emmanuella Apuri (…)2026-07-24
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Challenges and Solutions in Implementing Prehospital Emergency Accreditation from the Perspective of Executive Evaluators: A Qualitative Study

This qualitative study of 15 executive evaluators reveals that implementing prehospital emergency accreditation in Iran faces multidimensional challenges, particularly managerial issues and misaligned indicators during the implementation phase, necessitating organizational strengthening and indicator revisions to improve effectiveness.

Jafar Jalili shahmansouri, Amin Torabipour, Mohammad Mohseni2026-07-24
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Design and Characterization of a Multifunctional Hydrogel Membrane with Antioxidant, Antibacterial, and Bioactive Properties for Therapeutic and Periodontal Regeneration Purposes

This study presents a multifunctional, biodegradable hydrogel membrane composed of chitosan, gallic acid-grafted gelatin, and silver- and strontium-doped 45S5 bioactive glass that exhibits enhanced antioxidant, antibacterial, and osteogenic properties, demonstrating excellent cytocompatibility and potential for advanced periodontal regeneration.

Ahmad Qarebigloo, Mehdi Doosti-Telgerd, Seyed Amin Mousavi, Azin Khorramdel2026-07-24