959 papers
This study evaluated the delayed 7-1-7 surveillance response and identified significant environmental and behavioral risk factors associated with a severe *Plasmodium falciparum* malaria outbreak in Loma District, Southwest Ethiopia, in 2024.
This retrospective cohort study of over 300,000 total hip arthroplasty cases found that while deep learning models outperformed simple statistical approaches in predicting surgical duration and length of stay with lower mean absolute error, the resulting gains in clinically relevant operational accuracy were minimal, suggesting that patient-level data alone may have reached a practical ceiling for improving resource utilization in standardized procedures.
This study introduces the REACT score, a novel, low-cost prognostic model integrating preoperative inflammatory markers (NLR, SII), CEA levels, and pathological features (ENE, pT stage) to effectively stratify recurrence risk and predict disease-free survival in rectal cancer patients following neoadjuvant chemoradiotherapy and surgery.
This scoping review of 11 studies reveals a significant gap in validated bedside screening tools for older adults with dementia, finding strong evidence for malnutrition and feeding assessments, limited evidence for dysphagia, and a complete absence of validated sarcopenia instruments, thereby highlighting the urgent need for dementia-specific, multi-domain screening solutions.
This metagenomic study reveals that patients with systemic sclerosis exhibit distinct gut microbial dysbiosis characterized by an enrichment of oral-associated bacteria, a depletion of butyrate-producing species, and altered metabolic pathways, which correlate with specific clinical phenotypes.
In a single-center retrospective cohort study of 2,397 adults with acute ischemic stroke, greater early diastolic blood pressure variability within the first 72 hours was independently associated with an increased risk of in-hospital acute kidney injury, suggesting it may serve as a useful marker for risk stratification.
This cross-sectional study of 300 family caregivers in Odisha, India, reveals that while most possess moderate knowledge of palliative care, the prevailing neutral attitudes highlight an urgent need for structured educational interventions to improve service utilization.
This randomized controlled trial found that a nurse-supervised intradialytic isotonic exercise program significantly improved happiness in hemodialysis patients over eight weeks, though it did not yield significant improvements in appetite or dialysis adequacy.
This cross-sectional study of 2,924 patients with ischemic heart disease reveals that while longer disease duration is independently associated with gastric hyperemia, age remains the dominant predictor for most other endoscopic gastric abnormalities, including atrophy, hyperplasia, and esophagitis.
This study demonstrates that host-derived catecholamines differentially regulate bacterial growth and biofilm formation in a species-specific manner, with epinephrine and norepinephrine significantly enhancing proliferation and biofilm development in Gram-negative *E. coli* strains compared to the modest effects observed in Gram-positive *S. aureus*.