🧬 biology

Multitechnique characterisation of gut microbiota dynamics in piglets supplemented with Limosilactobacillus reuteri DSPV002C

This exploratory study found that supplementing weaned piglets with *Limosilactobacillus reuteri* DSPV002C led to the strain's persistence and temporal shifts in gut microbial composition, though significant differences in overall diversity or predicted metabolic pathways were not observed, likely due to the small sample size.

Jorge Alberto Zimmermann, Constanza Stoppani, Florencia Aylen Lencina, Nestor Denis Portela, Maria Julia Ruiz, Luis Manu (…)2026-07-01
🧬 biology

Free-ranging wild boars exhibit elevated circulating IL-6 concentrations compared with domestic pigs from Mediterranean ecosystem

This study demonstrates that free-ranging wild boars in a Mediterranean ecosystem exhibit significantly elevated circulating IL-6 concentrations compared to intensively reared domestic pigs, identifying IL-6 as a robust immune marker reflecting the distinct inflammatory tone shaped by ecological conditions at the wildlife–livestock interface.

Lola Llobat, Pablo Barragán-Sánchez, Ana Lesta, Victor Lizana, Pablo Jesús Marín-García2026-07-01
🧬 biology

Specific cognitive-balance interference evoked by cognitive conflict resolution in two 2D Spatial Stroop tasks

This study demonstrates that while resolving cognitive conflict in 2D Spatial Stroop tasks reliably triggers transient reductions in force moment variability as a sign of shared processing capacity, the specific body axis affected does not strictly align with the direction of manual decision-making, suggesting that cognitive-balance interference is shaped by broader sensorimotor factors like attention shifts rather than just the decision frame of reference.

Leif Johannsen, Anton Koger, Heiko Maurer, Elisa Straub, Katja Pollak, Denise Nadine Stephan, Andrea Kiesel, Iring Koch (…)2026-07-01
🧬 biology

Diversification of the Corophiida amphipod silk-spinning systems

This study presents the first extensive comparative analysis of silk-spinning systems in 40 corophiidan amphipod species, revealing a conserved ancestral framework alongside multiple independent evolutionary origins of modified structures that co-evolved with strong attachment silk, thereby establishing these crustaceans as a critical model for understanding the diversification of silk-spinning systems beyond insects and spiders.

Siena McKim, Brittany Cummings, Siena Waldman, Antonia Johnstone, Adam Wall, Kevin Kocot, Thomas Turner2026-07-01
🧬 biology

Lethal and sublethal effects of three mosquito larvicides on the endangered Romer’s Tree Frog (Liuixalus romeri): implications for urban mosquito control

This study demonstrates that while larvicidal oil poses a severe lethal and sublethal threat to the endangered Romer's Tree Frog, Bacillus thuringiensis israelensis (Bti) and temephos are safer alternatives for urban mosquito control, highlighting the critical need to evaluate both acute and prolonged exposure effects in ecological risk assessments.

Yik-Hei Sung, Hiu Nam Kong, Alex Hua Bing Liu, Hiu Ching Yuen, Franco Ka Wah Leung, Amy Wing Lam Fok, Tin Yan Hui, Micha (…)2026-07-01
🧬 biology

Enhanced extracellular invertase production in Bacillus subtilis by boosting synthesis and secretion in a suitable chassis cell

This study reports the first successful expression of the raffinose-hydrolyzing enzyme InvDz13 in *Bacillus subtilis*, achieving a record-high extracellular activity of 568.86 U/mL through a multidimensional combinatorial strategy involving chassis engineering, promoter optimization, signal peptide screening, and secretion pathway regulation.

Dongbang Yao, Yuanyuan chen, Longwei Que, Jiaru Qi, Fangmin Gu, Wei Fang, Zemin Fang, Juanjuan Liu, Yazhong Xiao2026-07-01
🧬 biology

Functional analysis of grapevine phosphoenolpyruvate carboxylase kinases (VvPPCKs) reveals a new role as regulators of the defence response and induction of resveratrol production in grapevine cells under elicitation

This study demonstrates that in grapevine cells, the overexpression of phosphoenolpyruvate carboxylase kinases (VvPPCKs) enhances PEPC activity while negatively regulating the stress-induced biosynthesis of the defense compound resveratrol, whereas silencing these kinases has the opposite effect.

Elías Hurtado-Gaitán, Ascensión Martínez-Márquez, María José Martínez-Esteso, Jaime Alfredo Morante-Carriel, James Hartw (…)2026-07-01
🧬 biology

R1398 is the GTP-𝛾-phosphate sensor that drives the ROC G-domain switching mechanism unique to Parkinson's disease-associated LRRK2

This study identifies the R1398 residue as a critical GTP-γ-phosphate sensor that regulates the conformational switching of the LRRK2 ROC domain, demonstrating that the protective R1398H mutation stabilizes an inactive GDP-bound state by impairing GTP-state stabilization and offering a novel therapeutic strategy for Parkinson's disease targeting the GTPase domain rather than the kinase active site.

Quyen Hoang, Yangshin Park, Chunxiang Wu, Rajnesh Yadav, Kayla Tennessen, Neo Hoang, Cardea Hoang, Xylena Reed, Xiaorong (…)2026-07-01