3918 papers
This study demonstrates that the territorial calls of Blue Petrels on Diego Ramírez Island exhibit distinct sexual differences, particularly in the number of elements and delta time, while also revealing significant individual vocal signatures and intrapopulation acoustic variation.
This study utilizes single-cell RNA sequencing and bioinformatics analysis to identify key immune-related biomarkers, regulatory networks, and potential therapeutic targets for Parkinson's disease, thereby advancing the understanding of its inflammatory pathogenesis.
This paper introduces a zero-point-constrained gray-box framework that uniquely identifies physical connection weights in coupled oscillator networks, enabling the reconstruction of dynamics and accurate prediction of structural perturbation responses without retraining.
The paper introduces FORCE, a forward modeling framework that simulates biologically plausible intra-voxel configurations to directly match diffusion MRI signals, thereby unifying the resolution of fiber crossings, generation of microstructural maps, and estimation of uncertainty in a single, efficient process without requiring specialized acquisitions.
This study identifies the histone variant H2A.B.3 as a critical chromatin-linked regulator that, in conjunction with UPF1, directs a novel nuclear RNA decay pathway to ensure the timely degradation of histone mRNAs during spermatogenesis and proper sperm chromatin remodeling.
This study utilizes a two-stage Korean WES–WGS framework to demonstrate that while high discrimination in Alzheimer's disease models is driven by diagnostic-proximal clinical variables and APOE signals, Non-APOE candidate variants identified in clinically enriched cohorts should be treated as hypothesis-generating features rather than confirmed independent predictors due to weak standalone predictive power and the lack of external replication.
This study presents the assembly and evolutionary analysis of the *Thalassia testudinum* chloroplast genome from Guánica, Puerto Rico, revealing high genetic conservation across *Thalassia* species and confirming its close phylogenetic relationship with Florida populations through long-read sequencing and comparative genomic methods.
This study demonstrates that repurposing cost-effective short-read sequencing data from diverse tomato lines can uncover over 71,000 high-confidence structural variants, revealing them as critical, previously hidden drivers of genetic diversity that enhance breeding workflows and resolve lineage relationships without requiring additional long-read sequencing investments.
This study presents a hybrid computational framework combining stochastic spatial point processes and explainable 3D deep learning to reveal that while global microglial distribution remains unchanged in Parkinson's disease, there is a significant, region-specific increase in microglial-pSyn co-occupancy in the substantia nigra driven by distinct micro-morphological texture gradients.
This study proposes an alignment-free phylogenetic analysis framework that integrates k-mer statistics with DNA physicochemical properties and strand symmetry into a feature vector, which is then optimized using an enhanced rough set-based selection method to achieve efficient and interpretable whole-genome evolutionary inference.