1816 papers
This study utilizes scanning electron microscopy and phylogenetic analyses of 20 Pakistani Boraginaceae species to demonstrate that while diverse seed morphological and micromorphological traits are effective for species-level identification, their evolutionary lability and high homoplasy limit their utility for higher taxonomic classification.
This study of 451 Egyptian children reveals that *Giardia duodenalis* transmission is predominantly anthroponotic, with Assemblage A exhibiting a clonal, human-adapted structure and Assemblage B showing greater genetic diversity, collectively indicating that public health interventions should prioritize interrupting human-to-human spread among young children.
This study integrates single-cell and transcriptome analyses to reveal that microglial phagocytic reprogramming, driven by the upregulation of Axl, evolves through distinct temporal phases during neuropathic pain progression and serves as a critical mechanism for sustaining chronic pain, suggesting Axl inhibition as a potential therapeutic strategy.
This study characterizes the distinct rhizosphere microbial community structure of *Taraxacum koksaghyz* in Xinjiang's saline-alkaline soils, revealing that while bacterial diversity decreases with increasing salinity, specific halotolerant bacteria and stress-tolerant fungi are enriched in response to varying ion compositions and nutrient availability, offering insights for improving crop yields in such environments.
This study demonstrates that developmental heat stress in male *Aedes aegypti* mosquitoes impairs their reproductive fitness and significantly disrupts their ability to induce normal female post-mating responses, leading to increased remating and reduced sperm storage, with potential implications for vector control programs under warming environmental conditions.
This study utilizes single-cell ATAC-seq combined with genetic barcoding to link diverse functional manipulations of CAR T cells to their specific chromatin signatures, revealing how cytokine concentrations and CAR design influence transcription factor activities and differentiation programs to enhance therapeutic efficacy.
This study demonstrates that the tonotopic differentiation of Kv1.1 expression in the avian cochlear nucleus is driven by a region-specific maturation of Ca2+-dependent cAMP signaling, which mediates activity-dependent upregulation of Kv1.1 specifically in high-frequency neurons around hatching to ensure precise auditory processing.
This bibliometric analysis of 886 publications reveals that global research on the tumor immune microenvironment in esophageal cancer has accelerated since 2020, shifting from basic immune infiltration studies toward clinical translation focused on immunosuppressive mechanisms, immunotherapy, and precision medicine strategies.
This large quasi-experimental study demonstrates that an 8-week, equipment-light Speed, Agility, and Quickness (SAQ) program embedded in regular physical education significantly improved 50-meter sprint performance among primary school children compared to routine instruction, supporting its feasibility as a pragmatic approach to enhance speed-related fitness in school settings.
This study reveals that the enhanced starch digestion capability in dogs originated through adaptive introgression from African golden wolves approximately 20,000 to 25,000 years ago, followed by positive selection around 7,500 years ago to accommodate the starch-rich diets of emerging human agricultural societies.