🧬 biology

Regulation of a symbiotic species network by a Megalomyrmex guest ant parasite: Establishment, maintenance, and threat of breakdown

This study reveals how the social parasite *Megalomyrmex symmetochus* infiltrates and stabilizes its host's symbiotic network by eavesdropping on chemical signals for nest location and alarm responses, while simultaneously utilizing its antimicrobial venom to regulate the microbial community.

Alissa R. Geisse, Blake S. Bringhurst, Aryel C. Goes, Ana R. Martinez, Sabrina Amador-Vargas, Lillian A. Brennan, Rachel (…)2026-06-29
🧬 biology

Extruded blue corn and tepary beans-based tortillas’ impact on obesity and gut microbiota in vivo

This study demonstrates that in Wistar rats, tortillas made from extruded blue corn and tepary beans improve gut microbiota diversity and lower total cholesterol without worsening dyslipidemia, offering a potential dietary strategy to mitigate obesity-related metabolic issues.

Guadalupe M. Perez-Guerrero, Cuauhtémoc Reyes-Moreno, Nuria Elizabeth Rocha-Guzmán, Edith Oliva Cuevas-Rodriguez, Mariel (…)2026-06-29
🧬 biology

Identification of Acetylation-Related Gene Biomarkers for Gallbladder Carcinoma via Multi-dataset and Machine Learning, with Insights into Immune Microenvironment Modulation

This study identifies seven acetylation-related gene biomarkers for Gallbladder Carcinoma using machine learning to construct a high-accuracy diagnostic model and reveals their significant associations with immune cell infiltration, particularly highlighting NCOA1's link to activated natural killer cells.

Yecheng Wang, Dongbin Liu, Yaming Zheng, Kuo Liang, Minghao Sui, Xiang Gao2026-06-29
🧬 biology

Microvesicles derived from follicular fluid and seminal plasma modulate human sperm quality after vitrification: Functional and molecular parameters based Assessment

This study demonstrates that supplementing human sperm vitrification media with high doses of raw follicular fluid or seminal plasma, or low doses of their derived microvesicles, significantly mitigates cryodamage by enhancing sperm motility, membrane integrity, and antioxidant capacity while reducing oxidative stress and apoptosis-related gene expression.

Morteza Taravat, Mustafa Numan Bucak, Reza Asadpour, Zahra Karimi, Mohammad saber Maroufi, Hojat Ghasemnejad, Tohid Reza (…)2026-06-29
🧬 biology

Adrenergic nerves regulate B cell responses to large antigens through modulation of lymph node permeability

Local adrenergic nerves are essential for optimal B cell responses to large antigens by regulating the remodeling of the lymph node's reticulin fiber network to increase permeability, a mechanism that may explain the increased susceptibility to infection in patients with nerve injuries.

Maureen Cox, Jessica Reel, Jumana Abbadi, Sydney Honold, Happy Agarwal, Rohit Singh, Jacob Farriester, Hunter Abrahamsen (…)2026-06-29
🧬 biology

Retinoic acid controls development and detoxification responses in the mussel Mytilus galloprovincialis despite loss of canonical RAR activity

Despite the loss of canonical retinoic acid receptor (RAR) transactivation activity in the Mediterranean mussel *Mytilus galloprovincialis*, exogenous retinoic acid still regulates development and induces detoxification gene expression, revealing an evolutionarily conserved mechanism for managing retinoic acid exposure that operates independently of the traditional RAR signaling pathway.

Enrico D'Aniello, Federica Salatiello, Angelica Miglioli, Rosa Maria Vitale, Valeria Tarallo, Giovanna Benvenuto, Samuel (…)2026-06-29
🧬 biology

A unified framework for the systematic detection of microproteins in standard proteomics workflows using a Ribo-seq informed transcriptomic language model

This paper presents a unified framework that integrates a Ribo-seq-informed transcriptomic language model with standard mass spectrometry workflows to systematically detect microproteins from non-canonical open reading frames without requiring specialized experimental protocols.

Nicolas Provencher, Sébastien Leblanc, Jean-François Jacques, Xavier Roucou2026-06-29