q-bio papers | Gist.Science

PerfuRange: feasible-set identifiability analysis of component blood flow in dual-input perfusion using a groundtruth digital phantom

This paper introduces PerfuRange, a framework that quantifies the identifiability of component blood flow in dual-input perfusion by determining the feasible range of physiological targets compatible with specific acquisition and modeling constraints, revealing that good model fits often fail to guarantee correct physiological decomposition due to inherent limitations in data and model assumptions.

Tomoki Saka2026-08-24

🧬 biology

Digital Dermatoglyphic Minutiae Patterns and Gross Motor Coordination Performance Among Undergraduate Students in a Nigerian Faculty of Basic Medical Sciences: A Descriptive Cross-Sectional Study

This descriptive cross-sectional study of 60 Nigerian undergraduate students found that while digital dermatoglyphic minutiae exhibited a consistent, quadrant-specific distribution pattern, there was no statistically significant association between these fingerprint characteristics and performance on a standardized rope-skipping task used to assess gross motor coordination.

Ijeoma Okpaleke, Professor Adenowo Thomas Kehinde2026-08-24

🧬 biology

Novel natural history notes from three nests of the vulnerable Tawny-chested Flycatcher (Aphanotriccus capitalis)

This paper documents novel natural history details from three Tawny-chested Flycatcher nests in Costa Rica, providing new insights into the species' breeding biology, nest characteristics, and parental care to support conservation efforts for this vulnerable bird.

Dallas Robert Levey, Tyler Wenzel, Jeisson Figueroa Sandi2026-08-24

🧬 biology

Estimating VO2max in patients with obesity using machine learning: A retrospective observational cohort study

This retrospective study demonstrates that machine learning models, particularly Bayesian Ridge Regression and Automatic Relevance Determination, can effectively estimate VO2max in adults with obesity using accessible physiological inputs, offering a promising alternative to traditional testing despite a remaining accuracy gap compared to direct measurements.

Bjørn-Jostein Singstad, Vimala Nunavath, Inge Rasmus Groote, Jens Kristoffer Hertel, Jarle Berge2026-08-24

🧬 biology

The reset of aging counters in the germline and early embryo: a systematic review of centriole, telomere, mitochondrial, and epigenetic clocks across seven developmental transitions

This systematic review synthesizes quantitative evidence demonstrating that four distinct cellular aging counters—centrioles, telomeres, mitochondria, and the epigenome—undergo coordinated resets across seven developmental transitions from primordial germ cells to the blastocyst, converging on a single re-establishment boundary that suggests a unified germline rejuvenation mechanism.

Jaba Tqemaladze2026-08-24

🧬 biology

Computational Identification and Prioritization of Conserved HIV-1 p24 Peptide Candidates

This study presents a reproducible computational pipeline that analyzed 185 HIV-1 p24 sequences to identify and prioritize 21 highly conserved peptide candidates, including a top MHC-I epitope with 98.4% sequence coverage, for potential vaccine development.

Sepideh Moafi2026-08-24

🧬 biology

Metataxonomic analysis of rectal samples of synanthropic bats from Montes Claros, Brazil

This study characterizes the gut microbiomes of eight synanthropic bat species in Montes Claros, Brazil, using 16S rRNA sequencing to identify predominant bacterial phyla, detect 34 potentially pathogenic genera, and report novel microbiota data for four species, thereby highlighting the importance of a One Health approach to bat-associated microbial risks.

Amanda Carvalho Rosado Ferreira, Vinicius José Moreira Nogueira, Bruno Borges Silva, Natália Carrillo Gaeta, Marcos Brya (…)2026-08-24

🧬 biology

Metabolic rewiring promotes metastasis while enhancing NK cell recognition

This study reveals that forcing cancer cells to switch to fatty acid oxidation via DCA treatment simultaneously promotes metastasis through EMT activation while enhancing their susceptibility to Natural Killer cell-mediated surveillance, identifying a metabolic vulnerability in metastatic cells.

Sara Zemiti, Susana Prieto, Steffy Escayg, Benjamin Hay, Amel Bouzid, Catherine Alexia, Carine Jacquard, Noemie Dudzinsk (…)2026-08-24

🧬 biology

GlycoRNA-associated miR-1228-3p promotes malignant progression of laryngeal squamous cell carcinoma by targeting SOX17

This study identifies GlycoRNA-associated miR-1228-3p as a novel driver of laryngeal squamous cell carcinoma progression that functions by directly targeting and suppressing SOX17 to activate the Wnt/β-catenin signaling pathway.

peng wang, zuer liu, shuo liu, baiying liu, xiang li, yanan sun2026-08-24

🧬 biology

Conserved Vibrio Repeats (VXRs) mediate horizontal transfer of superintegron-associated antibiotic resistance genes across Vibrio species

This study demonstrates that conserved Vibrio repeats (VXRs), primarily originating from the Cholera clade, facilitate the horizontal transfer of superintegron-associated antibiotic resistance genes across diverse Vibrio species, establishing these genomic elements as active reservoirs for the spread of antimicrobial resistance.

Sergio Morgado, Erica Fonseca, Ana Carolina Vicente2026-08-24

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