🧬 biology

Intraspecific variation in mycorrhiza-associated traits predicts plant growth and stress tolerance under resource limitation

This study demonstrates that intraspecific variation in pre-existing arbuscular mycorrhizal fungal colonization patterns and associated root traits, such as root diameter and tissue density, is critical for predicting drought and nutrient stress tolerance in alfalfa and sainfoin.

SUMA GHOSH, John Paul Wasan, Lysandra Pyle, Bill Biligetu, Jonathan Bennett2026-06-25
🧬 biology

Effect of smoke-derived compounds on the germination of Cerrado ground layer species

This study demonstrates that smoke-derived compounds, specifically karrikin 1 and mandelonitrile cyanohydrin, can stimulate or inhibit the germination of Cerrado ground-layer species in a concentration- and species-dependent manner, offering potential applications for ecological restoration.

Gabriel Schmidt Teixeira Motta, Heloiza Lourenço Zirondi, Jake O. Chandler, Tina Steinbrecher, Gerhard Leubner-Metzger (…)2026-06-25
🧬 biology

ISGylation of STING contributes to neuroinflammation and neurodegeneration via activating c-Fos in Parkinson's disease models

This study demonstrates that ISGylation of STING drives neuroinflammation and dopaminergic neuronal death in Parkinson's disease models by activating c-Fos through a positive feedback loop, suggesting that targeting this ISG15-STING axis offers a novel therapeutic strategy.

Xuan Liu, Shuzhen Xu, Pinyuan Huang, Xueer Jiang, Aiwen Dong, Tingjue Wu, Tianwen Huang, Qinyong Ye, En Huang2026-06-25
🧬 biology

Quantifying Lifetime Brain-Injury Burden Across Six Contact Sports: A Normalized Head-Impact Dose Model Integrating Exposure Frequency, Rotational Acceleration, and Cumulative Vulnerability

This paper introduces a transparent, reproducible computational model called the Normalized Head-Impact Dose (HID) that integrates impact frequency, rotational acceleration, and cumulative vulnerability to estimate and compare lifetime brain-injury burdens across six contact sports, revealing that combat sports carry the highest risk while providing a forward-looking framework for assessing neurodegenerative exposure with quantified uncertainty.

Richard Clark Kaufman2026-06-25
🧬 biology

Optic Disc Colour Ratio: A Fundus Pigmentation Proxy for Subgroup Fairness Analysis in Diabetic Retinopathy Screening

This paper introduces the Optic Disc Colour Ratio (ODCR) as a label-free proxy for fundus pigmentation to reveal that diabetic retinopathy screening models systematically assign higher referral probabilities to dark-pigmented fundi due to reduced vessel-background contrast, a disparity driven by sensitivity-calibrated decision rules that remains invisible to standard AUC metrics but is critical for fairness auditing.

Aaron Ajit2026-06-25
🧬 biology

Coexistence in Regenerating Forests: Activity Budgets, Vertical Stratification, and Habitat Use among Three Neotropical Primates

This study demonstrates that regenerating forests at La Selva, Costa Rica, can support high densities of mantled howler monkeys, Central American spider monkeys, and Panamanian white-throated capuchins while maintaining their coexistence through distinct activity budgets and vertical space use despite overlapping habitat preferences.

Susan M Howell, Richard Jensch, Orlando Vargas Ramirez, Enrique Alonso Castro Fonseca, Melissa Seaboch2026-06-25