🧬 Category

q-bio

4244 papers

🧬 biology

Multidimensional EEG Representations and Classification of Grip- Force-Level Motor Imagery

This study demonstrates that motor imagery at varying grip-force levels produces distinct neural representations across slow cortical potentials, sensorimotor rhythms, and directional functional networks, which can be effectively decoded by the EEGSym model to achieve classification accuracies significantly above chance, thereby enabling the development of force-graded control systems for rehabilitation and prosthetics.

Yan Bian, Zhao Jialing, Tian Linqing, Yu Xinting, Jian Dong2026-08-05
🧬 biology

Tree proximity dominates meter-scale microbial activity beneath mature Faidherbia albida trees on a sandy tropical soil in Zambia: evidence from spatial regression and blocked validation

This study demonstrates that in a Zambian sandy soil, proximity to mature *Faidherbia albida* trees is the primary driver of meter-scale microbial activity gradients, with soil organic carbon acting as a partial mediating pathway, though texture and pH offer no independent predictive value.

Elijah Phiri¹, Patience Chanda¹, Alice Mutiti Mweetwa¹2026-08-05
🧬 biology

Functional and genomic characterization of a Tsw resistance-breaking tomato spotted wilt virus isolate reveals diversification of the NSs avirulence determinant

This study characterizes a Tsw resistance-breaking TSWV isolate from Texas, demonstrating that while the viral movement protein NSm remains highly conserved, diversification of the NSs protein specifically enables the virus to evade Tsw-mediated recognition in pepper without overcoming Sw-5b resistance in tomato.

Surender Kumar, Rahul Mohan Singh, Kiran R. Gadhave2026-08-05
🧬 biology

Identification of a novel circular RNA specific to the bovine placenta from the pregnancy-associated glycoprotein gene

This study establishes an early-gestation bovine placental circRNA atlas and identifies a novel, placenta-specific circular RNA derived from the pregnancy-associated glycoprotein 4 gene (bta_circ_2423) that potentially regulates placental function by acting as a sponge for specific microRNAs.

Natsuki Asami, Masato Saito, Tasmina Akter, Hitomi Yoshino, Tomomi Kanazawa, Toshina Ishiguro-Oonuma, Keiichiro Kizaki2026-08-05
🧬 biology

IFNα8 drives STAT1-dependent HIV reactivation and persistence in memory CD4 T cells

This study identifies that IFNα8 drives HIV reactivation in memory CD4 T cells through a STAT1-dependent JAK–STAT signaling pathway, which simultaneously promotes viral transcription while enhancing anti-apoptotic mechanisms that support the long-term persistence of infected cells.

Leonard Mvaya, Caroline M Royle, Yunzhi Hong, Ming Luo, Yanran Zhao, Mark E Graham, Gabriel Duette, Monica M Saksena, Na (…)2026-08-05
🧬 biology

Power-Law Adaptation Stabilizes Primary Sensory Encoding of Natural Variance

This paper demonstrates that a multi-timescale sensory model utilizing a fractional memory tail (approximated by a three-pole system) effectively stabilizes primary sensory encoding against natural 1/fα1/f^\alpha environmental fluctuations by preventing refractory saturation and maintaining homeostatic firing rates, whereas simple single-exponential adaptation models fail under such conditions.

Stefan Bleeck2026-08-05
🧬 biology

A dual pronged approach to cancer immune exclusion: tumor-derived LAIR-1 simultaneously drives fibrosis and blocks immune recruitment in glioma

This study identifies tumor-derived LAIR-1 as a dual-function checkpoint in glioblastoma that simultaneously drives fibrosis and blocks immune cell recruitment via the SHP2/JNK pathway, and demonstrates that inhibiting this axis—either through genetic knockdown or pharmacological SHP2 inhibition—disassembles the extracellular matrix, recruits cytotoxic immune cells, and synergizes with gene therapy to achieve durable survival in preclinical models.

Pedro Lowenstein, Maria Luisa Varela, Henry Kast, Molly West, Marisa Rose, Daiana Perez Visnuk, Mary Springer, Sadhakshi (…)2026-08-05
🧬 biology

Vascular Basement Membranes Establish a β2-Integrin-Dependent Macrophage-Preadipocyte Niche that Guides Adipose Tissue Fate

This study reveals that vascular basement membrane laminins create a specialized niche where CD206-high Tim4+ macrophages interact with preadipocytes via β2-integrin to guide adipose tissue development, maintain structural integrity, and regulate metabolic homeostasis.

Lydia Sorokin, Luis Henrique Correa, Tiago Medeiros-Furquim, Tushar Deshpande, Laura Schnell, Dagmar Wachten, Yufang Shi (…)2026-08-05