4401 papers
This study reveals that entrapping *Synechocystis* sp. PCC 6803 in calcium-alginate hydrogels induces a coordinated, maintenance-oriented physiological state characterized by proteome remodeling toward stress protection and resource reallocation, which preserves photosynthetic activity and enables long-term resilience in photosynthetic living materials.
This study presents a pan-genome analysis of 23 highbush blueberry cultivars revealing that the glutathione S-transferase (GST) gene family exhibits an open pan-genome structure with significant structural variation and breeding-group divergence, ultimately identifying three Phi-class GSTs as the most credible candidates for regulating anthocyanin accumulation and fruit pigmentation.
This study presents a novel vulvovaginal candidiasis-on-chip model that successfully simulates the recruitment of neutrophils to Candida albicans-infected vaginal epithelium, enabling the investigation of the inflammatory mechanisms driving disease progression and serving as a platform for evaluating new therapies.
This study reports the isolation and genomic characterization of a multidrug-resistant, methicillin-resistant *Staphylococcus epidermidis* Sequence Type 280 from a skin lesion in an illegally traded rufous-bellied thrush, highlighting the role of urbanization and wildlife trade in the spread of antibiotic resistance within a One Health framework.
This study reveals that Cd34+ Pdgfra+ Telocytes (CPTCs) exhibit spatial heterogeneity across the ventral body wall, with superficial fascia-resident CPTCs functioning as a dynamic interfacial signaling hub that integrates skin and muscle compartments via Wnt and Nectin pathways to coordinate cross-layer communication.
This study identifies the dorsal bed nucleus of the stria terminalis (dBNST) as a critical forebrain hub where inflammation-activated neuronal ensembles and ATP-driven astrocytic signaling coordinate to modulate peripheral immune responses via a brain-spleen axis.
This study demonstrates that a polysaccharide extracted from the fibrous waste of the *Anacardium occidentale* pseudofruit possesses favorable physicochemical, biological, and structural properties, establishing it as a promising, sustainable biomaterial for developing biocompatible scaffolds.
This study demonstrates that patients with alcohol use disorder exhibit significantly reduced circulating levels of the perineuronal net components brevican and neurocan, which correlate with disease severity and chronicity, suggesting these proteoglycans serve as peripheral biomarkers of alcohol-induced neuroplastic disruption.
This study employs computational metabolomics to demonstrate that, beyond the traditionally emphasized diterpenoids, distinct flavonoid structural patterns serve as key drivers of species-specific chemical identity in the medicinal plants *Plectranthus hadiensis* and *Plectranthus ambiguus*.
This study reveals that metastatic cancer cells hijack vagal sensory neurons by utilizing the protein NINJ1 to activate a β-catenin-dependent repair program, thereby enhancing their ability to colonize distant tissues and identifying NINJ1 inhibition as a promising therapeutic strategy to block metastatic outgrowth.