4404 papers
This study demonstrates that maternal influenza infection triggers fibrinogen accumulation and microglial oxidative stress in the fetal mouse brain, leading to sex-biased apoptosis of neural progenitors, particularly in males, which may underlie adverse neurodevelopmental outcomes.
This study analyzes craniometric data from 335 skulls across four historical periods in Azerbaijan to identify epochal morphodynamic changes and develop discriminant functions for the preliminary chronological classification of human skulls.
This study demonstrates that the Antarctic bacterium *Flavobacterium azizsancarii* and the broader *Flavobacterium* genus exhibit a statistically significant, composition-adjusted excess of intergenic small open reading frames (sORFs) compared to null models, suggesting a genus-wide reservoir of potential sORFs rather than a strain-specific adaptation, though their functional translation and cold-adaptive roles remain unconfirmed.
This study evaluates the performance variations of RNaseR enzymes from four different vendors on RNA vaccine drug substance, demonstrating that digestion efficiency is significantly influenced by vendor source, incubation conditions, and buffer composition, with optimized formulations notably enhancing linear RNA degradation.
This study reveals that frequent recombination and insertion–deletion events across the Coronaviridae family have significantly shaped its genomic organization, diversification, and phylogeny, while simultaneously complicating efforts to forecast the emergence of novel pathogenic variants.
The paper introduces ATLAZ, a memory-deterministic geometric engine that utilizes Topological Data Analysis to bypass traditional bifurcating phylogenetic trees, enabling the precise detection of viral recombination, the confirmation of clonal descent, and the rapid identification of antiviral targets through topological metrics.
This two-step, two-sample Mendelian randomization study provides genetically supported evidence that specific gut microbiota, such as *Rhodanobacter*, causally increase breast cancer risk partially through the mediation of specific immune cell characteristics, notably CD25hi CD45RA+ CD4 non-Treg cells.
This paper proposes a structured framework for "virtual cell world models" (VCWMs) to address critical gaps between current capabilities and true world modeling by defining formal requirements, presenting empirical evidence of these shortcomings through three experiments, and outlining a staged roadmap with diagnostic capability ladders for developing multiscale, interactive cellular simulators.
This paper establishes that while the classical simulability of fermionic variational quantum algorithms is encoding-dependent and can be optimized via gauge transformations, their trainability is strictly encoding-invariant, implying that genuine quantum advantage must rely on encoding-independent resources like Lie algebra dimension and non-stabilizerness rather than encoding-specific metrics like Pauli weight.
This study documents the high diversity and endemism of Adjara's ephemeroid flora, identifies *Cyclamen adzharicum* as a key medicinal species, and reveals its leaves as a superior source of antioxidant-rich triterpenoid saponins compared to its tubers, thereby supporting conservation efforts and future pharmacological research.