4605 papers
This study demonstrates that the tonotopic differentiation of Kv1.1 expression in the avian cochlear nucleus is driven by a region-specific maturation of Ca2+-dependent cAMP signaling, which mediates activity-dependent upregulation of Kv1.1 specifically in high-frequency neurons around hatching to ensure precise auditory processing.
This bibliometric analysis of 886 publications reveals that global research on the tumor immune microenvironment in esophageal cancer has accelerated since 2020, shifting from basic immune infiltration studies toward clinical translation focused on immunosuppressive mechanisms, immunotherapy, and precision medicine strategies.
This large quasi-experimental study demonstrates that an 8-week, equipment-light Speed, Agility, and Quickness (SAQ) program embedded in regular physical education significantly improved 50-meter sprint performance among primary school children compared to routine instruction, supporting its feasibility as a pragmatic approach to enhance speed-related fitness in school settings.
This study reveals that the enhanced starch digestion capability in dogs originated through adaptive introgression from African golden wolves approximately 20,000 to 25,000 years ago, followed by positive selection around 7,500 years ago to accommodate the starch-rich diets of emerging human agricultural societies.
This study demonstrates that using water-soluble dye in rapid-curing silicone for cadaveric vascular perfusion produces superior results with bright, high-contrast vessels and no tissue staining compared to conventional fat-soluble dye methods, making it ideal for neuroanatomical teaching.
This study reveals how the social parasite *Megalomyrmex symmetochus* infiltrates and stabilizes its host's symbiotic network by eavesdropping on chemical signals for nest location and alarm responses, while simultaneously utilizing its antimicrobial venom to regulate the microbial community.
This study demonstrates that in Wistar rats, tortillas made from extruded blue corn and tepary beans improve gut microbiota diversity and lower total cholesterol without worsening dyslipidemia, offering a potential dietary strategy to mitigate obesity-related metabolic issues.
This study identifies seven acetylation-related gene biomarkers for Gallbladder Carcinoma using machine learning to construct a high-accuracy diagnostic model and reveals their significant associations with immune cell infiltration, particularly highlighting NCOA1's link to activated natural killer cells.
This study demonstrates that supplementing human sperm vitrification media with high doses of raw follicular fluid or seminal plasma, or low doses of their derived microvesicles, significantly mitigates cryodamage by enhancing sperm motility, membrane integrity, and antioxidant capacity while reducing oxidative stress and apoptosis-related gene expression.
Local adrenergic nerves are essential for optimal B cell responses to large antigens by regulating the remodeling of the lymph node's reticulin fiber network to increase permeability, a mechanism that may explain the increased susceptibility to infection in patients with nerve injuries.