Surgery represents one of the most dynamic frontiers in modern medicine, where precision, innovation, and human care converge to treat conditions that often defy other therapies. This field encompasses everything from minimally invasive procedures and robotic assistance to complex organ transplants and trauma care, constantly evolving as new technologies emerge to improve patient outcomes and recovery times.

On Gist.Science, we track every new preprint in this category as it appears on medRxiv, ensuring you stay ahead of the curve before formal publication. We process each submission to provide both plain-language explanations for broader understanding and detailed technical summaries for researchers, bridging the gap between raw data and actionable insight. Below are the latest papers in surgery, curated and summarized for clarity and depth.

🏥 surgery

Preoperative serum C-reactive protein and cholinesterase levels as risk factors of difficult laparoscopic cholecystectomy and severity of acute calculous cholecystitis: a retrospective observational study

This retrospective study of 198 patients undergoing early laparoscopic cholecystectomy for acute calculous cholecystitis identifies preoperative serum cholinesterase and C-reactive protein levels as independent predictors of difficult surgery, while C-reactive protein and male sex predict disease severity.

Kang, C.-Q., Chen, L.-P., Wang, Y.-X.2026-02-28
🏥 surgery

A prospective controled randomized multicenter study to evaluate severity of compensatory sweating after one-stage bilateral thoracic sympathectomy versus unilateral thoracic sympathectomy in the dominant side

This prospective randomized multicenter study demonstrates that while one-stage bilateral thoracic sympathectomy offers superior symptom control and quality-of-life improvements for primary palmar hyperhidrosis compared to unilateral surgery, it carries a significantly higher risk of severe compensatory sweating, supporting a staged approach where unilateral surgery may suffice for some patients.

Wolosker, M. B., Tedde, M. L., Noro Hamilton, N., Wolosker, N., Schmidt Aguiar, W. W., da Costa Ferreira, H. P., Westpha (…)2026-02-23
🏥 surgery

Normative Reference Values for the FACE-Q Skin Cancer Module: Patient Preoperative Scores and Comparison With Healthy Partners

This study establishes normative reference values for the FACE-Q Skin Cancer Module by demonstrating that preoperative scores of facial skin cancer patients are statistically equivalent to those of demographically matched healthy partners, thereby validating the module's utility for clinical interpretation while highlighting a specific sex-based difference in appearance scores.

Ottenhof, M. J.2026-02-16
🏥 surgery

Haptic Portable Robotic Device for Automated Guidewire or Catheter Navigation in Endovascular Procedures

This paper presents a lightweight, portable robotic system that utilizes servo current-based haptic feedback and impedance control to autonomously navigate guidewires through endovascular lesions by classifying tissue stiffness and adapting force application, thereby enhancing safety and accessibility in resource-limited settings.

Mohammadi, V., MacTaggart, J., Jadidi, M., Kamenskiy, A.2026-02-05