Preoperative serum C-reactive protein and cholinesterase levels as risk factors of difficult laparoscopic cholecystectomy and severity of acute calculous cholecystitis: a retrospective observational study
This retrospective study of 198 patients undergoing early laparoscopic cholecystectomy for acute calculous cholecystitis identifies preoperative serum cholinesterase and C-reactive protein levels as independent predictors of difficult surgery, while C-reactive protein and male sex predict disease severity.