📄 medicine

Environmental Salt Exposure, Salt-Taste Sensitivity and Genetic Variation in Hypertension-Mediated Organ Damage: A Cross-Sectional Study of 459 Untreated Adults in the Aral Sea Region

在一项针对高盐暴露的咸海地区459名未经治疗的高血压成年人的横断面研究中,较差的盐味感知与肾脏损伤密切相关,并被发现介导了AGTR1变异对肾脏结局影响中的显著遗传效应,这表明在资源有限的环境下,简单的床边味觉测试有助于识别高风险个体。

Khurshid Ataniyazov, Darya Zakirova, Gulnoz Khamidullaeva, Guzal Abdullaeva, Shahlo Turdikulova, Khurshid Fozilov, Alish (…)2026-09-07
📄 medicine

May Cancer Diagnostic Probe reduce re-operation rate in post-neoadjuvant breast cancer patients undergoing breast conserving surgery? A 5-year retrospective study

这项针对201例新辅助治疗后乳腺癌患者的五年回顾性研究表明,癌症诊断探针(CDP®)是一种更优越的手术中肿瘤边缘评估工具,与标准方法相比,其实现了97.8%的高阴性预测值和1.49%的低再手术率。

Mansour Nateghi, Afsaneh Momtaz, Zohreh Sadat Miripour, Marzieh Kamarehee, Mohammad Akbari, Atieh Akbari, Morteza Yousef (…)2026-09-07
📄 medicine

Pesticide Use Occupational Health Concerns and Perceived Aquatic Ecosystem Impacts among Farmers in the Lake Koka Irrigation System Ethiopia

这项研究表明,埃塞俄比亚科卡湖灌溉系统的农民频繁从事不安全的农药施用活动,且缺乏充分的防护措施,这导致了广泛的自我报告健康症状以及感知的当地水生生物多样性下降,从而凸显了对加强教育、培训和综合害虫管理策略的紧迫需求。

Mohammed Kasso, Fanose Kebede2026-09-07
📄 medicine

Clinical characteristics, imaging findings, and outcomes of gastrointestinal involvement in systemic lupus erythematosus: a retrospective case-control study

这项针对43例伴有胃肠道受累的系统性红斑狼疮(SLE)患者的回顾性病例对照研究表明,狼疮性肠系膜血管炎是其主要表现形式,其特征为特定的影像学发现和升高的D-二聚体水平,并且与尽管疾病整体活动度相似,但相比于无胃肠道并发症的SLE患者,其因感染导致的30天死亡率显著更高。

Teeradet Kasiban, Watcharin Wichapolchaiyakul, Ajchara Koolvisoot, Uayporn Kaosombatwattana2026-09-07
📄 medicine

Clinical, Echocardiographic and Angiographic Profile and Outcomes of Patients With Symptomatic Left Bundle Branch Block (LBBB): A Retrospective Observational Study From a Tertiary Care Center in Central India

这项针对印度中部某中心级医疗机构内 250 例伴有症状的左束支传导阻滞患者的回顾性研究表明,该病症与左心室功能障碍及阻塞性冠状动脉疾病密切相关,且高龄、糖尿病、心绞痛以及射血分数降低是预测冠状动脉阻塞和六个月死亡率增加的关键因素。

varun Mohod, Rupesh Agrawal, Sunil Washimkar2026-09-07
📄 medicine

Augmented Reality as a Home-Based, Ballet-Style Exercise Companion for Thai Older Adults: An Open-Data Assessment of Quality-of-Life Potential, Feasibility, and Public Attitudes

本文通过综合公开数据和以用户为中心的设计研究结果,评估了一款针对泰国老年人的增强现实芭蕾风格居家运动伴侣的可行性及其提升生活质量的潜力,旨在展示其在泰国超高龄社会背景下增强平衡能力、改善情绪及提升自主性的能力。

Waralak Vongdoiwang Siricharoen2026-09-07
📄 medicine

Safety and efficacy of pegfilgastim for the prophylaxis of chemotherapy-induced neutropenia: A prospective, observational, multicenter, single-arm study

这项在罗马尼亚开展的前瞻性、多中心、单臂研究表明,通过自注射器给药的非格列伯非格司(pegfilgrastim)在常规肿瘤临床实践中用于化疗诱导的中性粒细胞减少症的一级预防是安全、耐受性良好且有效的,其特征是发热性中性粒细胞减少症的发生率低且患者接受度高。

Michael Schenker, Andrei Ungureanu, Bogdan Gafton2026-09-07
📄 medicine

Factors associated with HIV infection among Adolescent Girls and Young Women aged 15-24 years enrolled in Adolescent Girls and Young Women program in Southern Province, Rwanda, 2025

这项针对卢旺达南部省1,275名青少年女性和年轻女性的2025年横断面研究表明,孤儿身份、性暴力、不一致的避孕套使用、注射类药物使用以及无法拒绝无保护性行为是与该人群中15.6%的艾滋病毒流行率相关的显著因素,凸显了对针对性心理社会、教育和预防干预措施的需求。

Alice MUSABYEYEZU, Judith KAMA MUKAMURIGO, Emmanuel NDAGIJIMANA2026-09-07